Abstract

Tuberculosis is one of the global public health concerns of morbidity and mortality. India shares large number of cases. Concurrent occurrence of HIV infection makes the treatment very difficult.Emergence of antitubercular (ATT) resistance is alarming due to limited number of safe and effective pharmacological agents. Newer agents are comparatively less efficacious and more toxic. Multi drug resistance, extensively drug resistance, and now total drug resistance tuberculosis create problem with conventional pharma cotherapy

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