Abstract

Gene Ontology-based semantic similarity (SS) allows the comparison of GO terms or entities annotated with GO terms, by leveraging on the ontology structure and properties and on annotation corpora. In the last decade the number and diversity of SS measures based on GO has grown considerably, and their application ranges from functional coherence evaluation, protein interaction prediction, and disease gene prioritization.

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DOI:
10.1007/978-1-4939-3743-1_12
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BibTeX key:
Pesquita2017
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