We evaluated the efficacy of various delay criteria (12.5\%, 25\%, 37.5\%, 5\%, 50\% delay) for motor milestone attainment to screen a sample of 173 high-risk preterm infants with gestational age < 32 weeks who had been sequentially followed for 18 to 24 months. Sensitivities were best with 12.5\% and 25\% delays, but specificities and positive predictive values were relatively lower. Since societal resources for evaluation and treatment of cerebral palsy are limited, the excellent specificities (81\% to 95\%) and positive predictive values (48\% to 85\%) with 50\% delay are more important than the somewhat lower sensitivities, especially since milestones involve a multistep screening process. Screening preterm infants by obtaining a history of motor milestone attainment with each child care visit, correcting for degree of prematurity, and using a 50\% delay criteria is a practical, inexpensive method of identifying infants at highest risk of cerebral palsy.
%0 Journal Article
%1 Allen1994
%A Allen, M. C.
%A Alexander, G. R.
%D 1994
%J J Perinatol
%K , Newborn; Cerebral Palsy; Data Interpretation, Statistical; Female; Gestational Age; Humans; Infant; Infant, Premature; Premature, Diseases; Male; Motor Skills; Neonatal Screening; Sensitivity and Specificity
%N 3
%P 190--193
%T Screening for cerebral palsy in preterm infants: delay criteria for motor milestone attainment.
%V 14
%X We evaluated the efficacy of various delay criteria (12.5\%, 25\%, 37.5\%, 5\%, 50\% delay) for motor milestone attainment to screen a sample of 173 high-risk preterm infants with gestational age < 32 weeks who had been sequentially followed for 18 to 24 months. Sensitivities were best with 12.5\% and 25\% delays, but specificities and positive predictive values were relatively lower. Since societal resources for evaluation and treatment of cerebral palsy are limited, the excellent specificities (81\% to 95\%) and positive predictive values (48\% to 85\%) with 50\% delay are more important than the somewhat lower sensitivities, especially since milestones involve a multistep screening process. Screening preterm infants by obtaining a history of motor milestone attainment with each child care visit, correcting for degree of prematurity, and using a 50\% delay criteria is a practical, inexpensive method of identifying infants at highest risk of cerebral palsy.
@article{Allen1994,
abstract = {We evaluated the efficacy of various delay criteria (12.5\%, 25\%, 37.5\%, 5\%, 50\% delay) for motor milestone attainment to screen a sample of 173 high-risk preterm infants with gestational age < 32 weeks who had been sequentially followed for 18 to 24 months. Sensitivities were best with 12.5\% and 25\% delays, but specificities and positive predictive values were relatively lower. Since societal resources for evaluation and treatment of cerebral palsy are limited, the excellent specificities (81\% to 95\%) and positive predictive values (48\% to 85\%) with 50\% delay are more important than the somewhat lower sensitivities, especially since milestones involve a multistep screening process. Screening preterm infants by obtaining a history of motor milestone attainment with each child care visit, correcting for degree of prematurity, and using a 50\% delay criteria is a practical, inexpensive method of identifying infants at highest risk of cerebral palsy.},
added-at = {2014-07-19T17:38:14.000+0200},
author = {Allen, M. C. and Alexander, G. R.},
biburl = {https://www.bibsonomy.org/bibtex/255584050b665232ee5d0ededc3e4dd9a/ar0berts},
groups = {public},
interhash = {2eed36af39e61aca6e2d8823fc379267},
intrahash = {55584050b665232ee5d0ededc3e4dd9a},
journal = {J Perinatol},
keywords = {, Newborn; Cerebral Palsy; Data Interpretation, Statistical; Female; Gestational Age; Humans; Infant; Infant, Premature; Premature, Diseases; Male; Motor Skills; Neonatal Screening; Sensitivity and Specificity},
number = 3,
pages = {190--193},
pmid = {8064421},
timestamp = {2014-07-19T17:38:14.000+0200},
title = {Screening for cerebral palsy in preterm infants: delay criteria for motor milestone attainment.},
username = {ar0berts},
volume = 14,
year = 1994
}