OBJECTIVE: To determine hip radiographic findings in children with cerebral palsy (CP) treated with botulinum toxin type A (BTX-A). DESIGN: Retrospective chart review with correlation to radiographic findings. SETTING: Academic center. PARTICIPANTS: Sixteen subjects with CP. INTERVENTION: BTX-A treatment to adductor muscles. MAIN OUTCOME MEASURE: The Reimers hip migration percentage before and after BTX-A. RESULTS: Thirty-two hips in 16 children with CP were treated. We examined the effect of initial migration percentage and initial migration percentage age on the change in migration percentage after BTX-A injection. A significant effect for initial migration percentage (<30\% or >/=30\%; F=19.05, P <.001) and a significant interaction between initial migration percentage and initial migration percentage age (F=7.5, P <.01) was noted. Initial migration percentage age (</=24 mo or >24 mo) was not significant (F=.95, P =.34). Patients who had an initial migration percentage of 30\% or more and were less than 24 months old were more likely to have a decrease in migration percentage after BTX-A injection compared with patients who were older than 24 months and who had an initial migration percentage of 30\% or more. CONCLUSIONS: Improvement in hip migration percentage after BTX-A injection is a function of age and the initial migration percentage. BTX-A injections to adductor muscles may be beneficial for some children with CP.
%0 Journal Article
%1 Pidcock2005
%A Pidcock, Frank S
%A Fish, David E
%A Johnson-Greene, Doug
%A Borras, Isabel
%A McGready, John
%A Silberstein, Charles E
%D 2005
%J Arch Phys Med Rehabil
%K Aging; Botulinum Toxin Type A; Cerebral Palsy; Child, Preschool; Female; Hip; Humans; Infant; Male; Neuromuscular Agents; Retrospective Studies
%N 3
%P 431--435
%R 10.1016/j.apmr.2004.03.034
%T Hip migration percentage in children with cerebral palsy treated with botulinum toxin type A.
%U http://dx.doi.org/10.1016/j.apmr.2004.03.034
%V 86
%X OBJECTIVE: To determine hip radiographic findings in children with cerebral palsy (CP) treated with botulinum toxin type A (BTX-A). DESIGN: Retrospective chart review with correlation to radiographic findings. SETTING: Academic center. PARTICIPANTS: Sixteen subjects with CP. INTERVENTION: BTX-A treatment to adductor muscles. MAIN OUTCOME MEASURE: The Reimers hip migration percentage before and after BTX-A. RESULTS: Thirty-two hips in 16 children with CP were treated. We examined the effect of initial migration percentage and initial migration percentage age on the change in migration percentage after BTX-A injection. A significant effect for initial migration percentage (<30\% or >/=30\%; F=19.05, P <.001) and a significant interaction between initial migration percentage and initial migration percentage age (F=7.5, P <.01) was noted. Initial migration percentage age (</=24 mo or >24 mo) was not significant (F=.95, P =.34). Patients who had an initial migration percentage of 30\% or more and were less than 24 months old were more likely to have a decrease in migration percentage after BTX-A injection compared with patients who were older than 24 months and who had an initial migration percentage of 30\% or more. CONCLUSIONS: Improvement in hip migration percentage after BTX-A injection is a function of age and the initial migration percentage. BTX-A injections to adductor muscles may be beneficial for some children with CP.
@article{Pidcock2005,
abstract = {OBJECTIVE: To determine hip radiographic findings in children with cerebral palsy (CP) treated with botulinum toxin type A (BTX-A). DESIGN: Retrospective chart review with correlation to radiographic findings. SETTING: Academic center. PARTICIPANTS: Sixteen subjects with CP. INTERVENTION: BTX-A treatment to adductor muscles. MAIN OUTCOME MEASURE: The Reimers hip migration percentage before and after BTX-A. RESULTS: Thirty-two hips in 16 children with CP were treated. We examined the effect of initial migration percentage and initial migration percentage age on the change in migration percentage after BTX-A injection. A significant effect for initial migration percentage (<30\% or >/=30\%; F=19.05, P <.001) and a significant interaction between initial migration percentage and initial migration percentage age (F=7.5, P <.01) was noted. Initial migration percentage age (</=24 mo or >24 mo) was not significant (F=.95, P =.34). Patients who had an initial migration percentage of 30\% or more and were less than 24 months old were more likely to have a decrease in migration percentage after BTX-A injection compared with patients who were older than 24 months and who had an initial migration percentage of 30\% or more. CONCLUSIONS: Improvement in hip migration percentage after BTX-A injection is a function of age and the initial migration percentage. BTX-A injections to adductor muscles may be beneficial for some children with CP.},
added-at = {2014-07-19T21:02:24.000+0200},
author = {Pidcock, Frank S and Fish, David E and Johnson-Greene, Doug and Borras, Isabel and McGready, John and Silberstein, Charles E},
biburl = {https://www.bibsonomy.org/bibtex/25f0992f82d486ff624a94cc913103f4c/ar0berts},
doi = {10.1016/j.apmr.2004.03.034},
groups = {public},
interhash = {b6718d544e28ff8fb5ad4cd63fc18a22},
intrahash = {5f0992f82d486ff624a94cc913103f4c},
journal = {Arch Phys Med Rehabil},
keywords = {Aging; Botulinum Toxin Type A; Cerebral Palsy; Child, Preschool; Female; Hip; Humans; Infant; Male; Neuromuscular Agents; Retrospective Studies},
month = Mar,
number = 3,
pages = {431--435},
pii = {S0003999304004794},
pmid = {15759224},
timestamp = {2014-07-19T21:02:24.000+0200},
title = {Hip migration percentage in children with cerebral palsy treated with botulinum toxin type A.},
url = {http://dx.doi.org/10.1016/j.apmr.2004.03.034},
username = {ar0berts},
volume = 86,
year = 2005
}