Signaling systems are exciting to study precisely because they are some of the most complex and dynamical systems that we know. The cell needs operational freedom and, thus, many motif-domain interactions might not be "hard-wired" through evolution, but instead may be like the Linux operating system, where symbolic links can point to files without duplication.
%0 Journal Article
%1 Linding2010Revolution
%A Linding, Rune
%D 2010
%J Sci. Signal.
%K complex-systems editorial regulatory-networks
%N 127
%P eg4+
%R 10.1126/scisignal.3127eg4
%T (R)evolution of Complex Regulatory Systems
%U http://dx.doi.org/10.1126/scisignal.3127eg4
%V 3
%X Signaling systems are exciting to study precisely because they are some of the most complex and dynamical systems that we know. The cell needs operational freedom and, thus, many motif-domain interactions might not be "hard-wired" through evolution, but instead may be like the Linux operating system, where symbolic links can point to files without duplication.
@article{Linding2010Revolution,
abstract = {Signaling systems are exciting to study precisely because they are some of the most complex and dynamical systems that we know. The cell needs operational freedom and, thus, many motif-domain interactions might not be "hard-wired" through evolution, but instead may be like the Linux operating system, where symbolic links can point to files without duplication.},
added-at = {2018-12-02T16:09:07.000+0100},
author = {Linding, Rune},
biburl = {https://www.bibsonomy.org/bibtex/267c6f78636fd7066de2645afc4bbe7c4/karthikraman},
citeulike-article-id = {7349890},
citeulike-linkout-0 = {http://dx.doi.org/10.1126/scisignal.3127eg4},
citeulike-linkout-1 = {http://view.ncbi.nlm.nih.gov/pubmed/20571125},
citeulike-linkout-2 = {http://www.hubmed.org/display.cgi?uids=20571125},
day = 22,
doi = {10.1126/scisignal.3127eg4},
interhash = {2e76cdfdc9aeb5bcc21dbae72ae97ba6},
intrahash = {67c6f78636fd7066de2645afc4bbe7c4},
issn = {1937-9145},
journal = {Sci. Signal.},
keywords = {complex-systems editorial regulatory-networks},
month = jun,
number = 127,
pages = {eg4+},
pmid = {20571125},
posted-at = {2010-06-25 10:34:48},
priority = {2},
timestamp = {2018-12-02T16:09:07.000+0100},
title = {(R)evolution of Complex Regulatory Systems},
url = {http://dx.doi.org/10.1126/scisignal.3127eg4},
volume = 3,
year = 2010
}