Article,

Five-year outcome of infants of birthweight 500 to 1500 grams: relationship with neonatal ultrasound data.

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Am J Perinatol, 7 (1): 60--65 (January 1990)

Abstract

Of 154 consecutive survivors of birthweight 500 to 1500 gm, 139 (90.3\%) were seen at 5 years of age, corrected for prematurity, and 137 (89\%) were able to be fully assessed by both the psychologist and pediatrician. All but two children had had serial cranial ultrasonography with a linear array real-time scanner in the neonatal period. At 5 years, of 39 children with cerebral ultrasound abnormalities detected during their primary hospitalization, seven (17.9\%) had cerebral palsy, but 32 (82.1\%) did not. A further three children with cerebral palsy at 5 years had had no cerebral abnormalities on ultrasound. Of the cerebral abnormalities diagnosed by ultrasound, ventricular dilation, with or without cerebroventricular hemorrhage, had the highest positive predictive value (40\%) for cerebral palsy at 5 years. In the 127 children free from cerebral palsy at 5 years, two (1.6\%) had severe intellectual impairment, both of whom had had normal cerebral ultrasonography. Although neonatal cranial ultrasonography with a linear array was somewhat predictive of cerebral palsy at 5 years, the majority of infants with abnormal scans had no severe sensorineural impairments at 5 years.

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