Purpose To investigate the potential of real-time magnetic
particle imaging (MPI) to guide percutaneous transluminal
angioplasty (PTA) of vascular stenoses in a phantom
model.
Materials and Methods Experiments were conducted on a
custom-built MPI scanner. Vascular stenosis phantoms
consisted of polyvinyl chloride tubes (inner diameter
8 mm) prepared with a centrally aligned cable tie to
form * 50% stenoses. MPI angiography for visualization
of stenoses was performed using the superparamagnetic
iron oxide nanoparticle-based contrast agent Ferucarbotran
(10 mmol (Fe)/l). Balloon catheters and guidewires for
PTA were visualized using custom-made lacquer markers
based on Ferucarbotran. Stenosis dilation (n = 3) was
performed by manually inflating the PTA balloon with
diluted Ferucarbotran. An online reconstruction framework
was implemented for real-time imaging with very short
latency time.
Results Visualization of stenosis phantoms and guidance
of interventional instruments in real-time (4 frames/
s, * 100 ms latency time) was possible using an online
reconstruction algorithm. Labeling of guidewires and balloon
catheters allowed for precise visualization of instrument
positions.
Conclusion Real-time MPI-guided PTA in a phantom
model is feasible.
%0 Journal Article
%1 Herz_2018
%A Herz, Stefan
%A Vogel, Patrick
%A Dietrich, Philipp
%A Kampf, Thomas
%A Rückert, Martin A.
%A Kickuth, Ralph
%A Behr, Volker C.
%A Bley, Thorsten A.
%D 2018
%J Cardiovasc Intervent Radiol
%K article mpi myown
%N 7
%P 1100-1105
%R 10.1007/s00270-018-1955-7
%T Magnetic Particle Imaging Guided Real-Time Percutaneous Transluminal Angioplasty in a Phantom Model
%V 41
%X Purpose To investigate the potential of real-time magnetic
particle imaging (MPI) to guide percutaneous transluminal
angioplasty (PTA) of vascular stenoses in a phantom
model.
Materials and Methods Experiments were conducted on a
custom-built MPI scanner. Vascular stenosis phantoms
consisted of polyvinyl chloride tubes (inner diameter
8 mm) prepared with a centrally aligned cable tie to
form * 50% stenoses. MPI angiography for visualization
of stenoses was performed using the superparamagnetic
iron oxide nanoparticle-based contrast agent Ferucarbotran
(10 mmol (Fe)/l). Balloon catheters and guidewires for
PTA were visualized using custom-made lacquer markers
based on Ferucarbotran. Stenosis dilation (n = 3) was
performed by manually inflating the PTA balloon with
diluted Ferucarbotran. An online reconstruction framework
was implemented for real-time imaging with very short
latency time.
Results Visualization of stenosis phantoms and guidance
of interventional instruments in real-time (4 frames/
s, * 100 ms latency time) was possible using an online
reconstruction algorithm. Labeling of guidewires and balloon
catheters allowed for precise visualization of instrument
positions.
Conclusion Real-time MPI-guided PTA in a phantom
model is feasible.
@article{Herz_2018,
abstract = {Purpose To investigate the potential of real-time magnetic
particle imaging (MPI) to guide percutaneous transluminal
angioplasty (PTA) of vascular stenoses in a phantom
model.
Materials and Methods Experiments were conducted on a
custom-built MPI scanner. Vascular stenosis phantoms
consisted of polyvinyl chloride tubes (inner diameter
8 mm) prepared with a centrally aligned cable tie to
form * 50% stenoses. MPI angiography for visualization
of stenoses was performed using the superparamagnetic
iron oxide nanoparticle-based contrast agent Ferucarbotran
(10 mmol (Fe)/l). Balloon catheters and guidewires for
PTA were visualized using custom-made lacquer markers
based on Ferucarbotran. Stenosis dilation (n = 3) was
performed by manually inflating the PTA balloon with
diluted Ferucarbotran. An online reconstruction framework
was implemented for real-time imaging with very short
latency time.
Results Visualization of stenosis phantoms and guidance
of interventional instruments in real-time (4 frames/
s, * 100 ms latency time) was possible using an online
reconstruction algorithm. Labeling of guidewires and balloon
catheters allowed for precise visualization of instrument
positions.
Conclusion Real-time MPI-guided PTA in a phantom
model is feasible.},
added-at = {2018-04-17T09:46:07.000+0200},
author = {Herz, Stefan and Vogel, Patrick and Dietrich, Philipp and Kampf, Thomas and Rückert, Martin A. and Kickuth, Ralph and Behr, Volker C. and Bley, Thorsten A.},
biburl = {https://www.bibsonomy.org/bibtex/2537bf5066bb144dac8f62d2c9e524a67/pvogel},
day = 16,
doi = {10.1007/s00270-018-1955-7},
interhash = {27a09de6c81837475edb4761e8be1674},
intrahash = {537bf5066bb144dac8f62d2c9e524a67},
issn = {0174-1551},
journal = {Cardiovasc Intervent Radiol},
keywords = {article mpi myown},
month = {april},
number = 7,
pages = {1100-1105},
timestamp = {2020-01-25T20:37:29.000+0100},
title = {Magnetic Particle Imaging Guided Real-Time Percutaneous Transluminal Angioplasty in a Phantom Model},
type = {Publication},
volume = 41,
year = 2018
}