In the following work, the vibrational spectroscopic characteristics of
artepillin C are reported by means of Fourier transform infrared (FT-IR)
and Raman spectroscopies, surface-enhanced Raman scattering (SERS), and
coherent anti-Stokes Raman scattering (CARS) microscopy. Artepillin C is
an interesting compound due to its pharmacological properties, including
antitumor activity. It is found as the major component of Brazilian
green propolis, a resinous mixture produced by bees to protect their
hives against intruders. Vibrational spectroscopic techniques have shown a strong peak at 1599 cm(-1), assigned to C=C stretching vibrations from
the aromatic ring of artepillin C. From these data, direct visualization
of artepillin C could be assessed by means of CARS microscopy, showing
differences in the film hydration obtained for its neutral and
deprotonated states. Raman-based methods show potential to visualize the
uptake and action of artepillin C in biological systems, triggering its
interaction with biological systems that are needed to understand its
mechanism of action.
%0 Journal Article
%1 WOS:000534500000001
%A Pazin, Wallance M
%A Furini, Leonardo N
%A Solovyeva, Vita
%A Lemma, Tibebe
%A Rubira, Rafael J G
%A Jorgensen, Bjarke
%A Constantino, Carlos J L
%A Brewer, Jonathan R
%C 2455 TELLER RD, THOUSAND OAKS, CA 91320 USA
%D 2020
%I SAGE PUBLICATIONS INC
%J APPLIED SPECTROSCOPY
%K C; CARS Raman SERS; imaging microscopy; propolis; scattering; spectroscopy; surface-enhanced techniques} {Artepillin
%N 7
%P 751-757
%R 10.1177/0003702820904456, Early Access Date = APR 2020
%T Vibrational Spectroscopic Characterization and Coherent Anti-Stokes
Raman Spectroscopy (CARS) Imaging of Artepillin C
%V 74
%X In the following work, the vibrational spectroscopic characteristics of
artepillin C are reported by means of Fourier transform infrared (FT-IR)
and Raman spectroscopies, surface-enhanced Raman scattering (SERS), and
coherent anti-Stokes Raman scattering (CARS) microscopy. Artepillin C is
an interesting compound due to its pharmacological properties, including
antitumor activity. It is found as the major component of Brazilian
green propolis, a resinous mixture produced by bees to protect their
hives against intruders. Vibrational spectroscopic techniques have shown a strong peak at 1599 cm(-1), assigned to C=C stretching vibrations from
the aromatic ring of artepillin C. From these data, direct visualization
of artepillin C could be assessed by means of CARS microscopy, showing
differences in the film hydration obtained for its neutral and
deprotonated states. Raman-based methods show potential to visualize the
uptake and action of artepillin C in biological systems, triggering its
interaction with biological systems that are needed to understand its
mechanism of action.
@article{WOS:000534500000001,
abstract = {In the following work, the vibrational spectroscopic characteristics of
artepillin C are reported by means of Fourier transform infrared (FT-IR)
and Raman spectroscopies, surface-enhanced Raman scattering (SERS), and
coherent anti-Stokes Raman scattering (CARS) microscopy. Artepillin C is
an interesting compound due to its pharmacological properties, including
antitumor activity. It is found as the major component of Brazilian
green propolis, a resinous mixture produced by bees to protect their
hives against intruders. Vibrational spectroscopic techniques have shown a strong peak at 1599 cm(-1), assigned to C=C stretching vibrations from
the aromatic ring of artepillin C. From these data, direct visualization
of artepillin C could be assessed by means of CARS microscopy, showing
differences in the film hydration obtained for its neutral and
deprotonated states. Raman-based methods show potential to visualize the
uptake and action of artepillin C in biological systems, triggering its
interaction with biological systems that are needed to understand its
mechanism of action.},
added-at = {2022-05-23T20:00:14.000+0200},
address = {2455 TELLER RD, THOUSAND OAKS, CA 91320 USA},
author = {Pazin, Wallance M and Furini, Leonardo N and Solovyeva, Vita and Lemma, Tibebe and Rubira, Rafael J G and Jorgensen, Bjarke and Constantino, Carlos J L and Brewer, Jonathan R},
biburl = {https://www.bibsonomy.org/bibtex/29d89178f7423bf1cad0f6aaf02ce03d9/ppgfis_ufc_br},
doi = {10.1177/0003702820904456, Early Access Date = APR 2020},
interhash = {78094d83134c5df4271a9c87f61a72a1},
intrahash = {9d89178f7423bf1cad0f6aaf02ce03d9},
issn = {0003-7028},
journal = {APPLIED SPECTROSCOPY},
keywords = {C; CARS Raman SERS; imaging microscopy; propolis; scattering; spectroscopy; surface-enhanced techniques} {Artepillin},
number = 7,
pages = {751-757},
publisher = {SAGE PUBLICATIONS INC},
pubstate = {published},
timestamp = {2022-05-23T20:00:14.000+0200},
title = {Vibrational Spectroscopic Characterization and Coherent Anti-Stokes
Raman Spectroscopy (CARS) Imaging of Artepillin C},
tppubtype = {article},
volume = 74,
year = 2020
}