Epidemic spread and antigenic variability of Neisseria meningitidis
M. Achtman. Trends in Microbiology, 3 (5):
186--92(May 1995)PMID: 7627456.
Abstract
Genetic variation of cell-surface antigens of serogroup A meningococci arises from horizontal genetic exchange. Most clonal variants are lost by clonal reduction during epidemic and pandemic spread, but in exceptional cases, genetic variants are rapidly fixed in the bacterial population by clonal replacement.
%0 Journal Article
%1 achtman_epidemic_1995
%A Achtman, M
%D 1995
%J Trends in Microbiology
%K Africa, Antigenic Antigens, Bacterial Bacterial, Disease Humans, Infections, Membrane Meningitis, Meningococcal Meningococcal, Neisseria Outbreaks, Outer Proteins, Serotyping Variation, Western, meningitidis,
%N 5
%P 186--92
%T Epidemic spread and antigenic variability of Neisseria meningitidis
%U http://www.ncbi.nlm.nih.gov/pubmed/7627456
%V 3
%X Genetic variation of cell-surface antigens of serogroup A meningococci arises from horizontal genetic exchange. Most clonal variants are lost by clonal reduction during epidemic and pandemic spread, but in exceptional cases, genetic variants are rapidly fixed in the bacterial population by clonal replacement.
@article{achtman_epidemic_1995,
abstract = {Genetic variation of cell-surface antigens of serogroup A meningococci arises from horizontal genetic exchange. Most clonal variants are lost by clonal reduction during epidemic and pandemic spread, but in exceptional cases, genetic variants are rapidly fixed in the bacterial population by clonal replacement.},
added-at = {2011-03-11T10:05:34.000+0100},
author = {Achtman, M},
biburl = {https://www.bibsonomy.org/bibtex/2aab8fd2393f2125535cae7e4489f76b0/jelias},
interhash = {2ca6dee697251f294dec7c0c7cee88b3},
intrahash = {aab8fd2393f2125535cae7e4489f76b0},
issn = {{0966-842X}},
journal = {Trends in Microbiology},
keywords = {Africa, Antigenic Antigens, Bacterial Bacterial, Disease Humans, Infections, Membrane Meningitis, Meningococcal Meningococcal, Neisseria Outbreaks, Outer Proteins, Serotyping Variation, Western, meningitidis,},
month = may,
note = {{PMID:} 7627456},
number = 5,
pages = {186--92},
timestamp = {2011-03-11T10:06:28.000+0100},
title = {Epidemic spread and antigenic variability of Neisseria meningitidis},
url = {http://www.ncbi.nlm.nih.gov/pubmed/7627456},
volume = 3,
year = 1995
}