@nmrresource

High-resolution \NMR\ spectroscopy of membrane proteins in aligned bicelles

, , , , , and . J. Am. Chem. Soc., 126 (47): 15340--15341 (December 2004)
DOI: 10.1021/ja045631y

Abstract

High-resolution solid-state NMR spectra can be obtained from uniformly (15)N-labeled membrane proteins in magnetically aligned bicelles. Fast uniaxial diffusion about the axis of the bilayer normal results in single-line spectra that contain the orientational information necessary for protein structure determination.

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