Diffusion Tensor Imaging (DTI) is a magnetic resonance imaging method
that can be used to measure local information about the structure
of white matter within the human brain. Combining DTI data with
the computational methods of MR tractography, neuroscientists can
estimate the locations and sizes of nerve bundles (white matter
pathways) that course through the human brain. Neuroscientists have
used visualization techniques to better understand tractography
data, but they often struggle with the abundance and complexity
of the pathways. In this paper, we describe a novel set of interaction
techniques that make it easier to explore and interpret such pathways.
Specifically, our application allows neuroscientists to place and
interactively manipulate box or ellipsoid-shaped regions to selectively
display pathways that pass through specific anatomical areas. These
regions can be used in coordination with a simple and flexible query
language which allows for arbitrary combinations of these queries
using Boolean logic operators. A representation of the cortical
surface is provided for specifying queries of pathways that may
be relevant to gray matter structures and for displaying activation
information obtained from functional magnetic resonance imaging.
By precomputing the pathways and their statistical properties, we
obtain the speed necessary for interactive question-and-answer sessions
with brain researchers. We survey some questions that researchers
have been asking about tractography data and show how our system
can be used to answer these questions efficiently.
%0 Journal Article
%1 Sherbondy2005
%A Sherbondy, A.
%A Akers, D.
%A Mackenzie, R.
%A Dougherty, R.
%A Wandell, B.
%D 2005
%J Visualization and Computer Graphics, IEEE Transactions on
%K Diffusion, Tensor DTI Imaging, Diffusion
%N 4
%P 419--430
%R 10.1109/TVCG.2005.59
%T Exploring connectivity of the brain's white matter with dynamic queries
%V 11
%X Diffusion Tensor Imaging (DTI) is a magnetic resonance imaging method
that can be used to measure local information about the structure
of white matter within the human brain. Combining DTI data with
the computational methods of MR tractography, neuroscientists can
estimate the locations and sizes of nerve bundles (white matter
pathways) that course through the human brain. Neuroscientists have
used visualization techniques to better understand tractography
data, but they often struggle with the abundance and complexity
of the pathways. In this paper, we describe a novel set of interaction
techniques that make it easier to explore and interpret such pathways.
Specifically, our application allows neuroscientists to place and
interactively manipulate box or ellipsoid-shaped regions to selectively
display pathways that pass through specific anatomical areas. These
regions can be used in coordination with a simple and flexible query
language which allows for arbitrary combinations of these queries
using Boolean logic operators. A representation of the cortical
surface is provided for specifying queries of pathways that may
be relevant to gray matter structures and for displaying activation
information obtained from functional magnetic resonance imaging.
By precomputing the pathways and their statistical properties, we
obtain the speed necessary for interactive question-and-answer sessions
with brain researchers. We survey some questions that researchers
have been asking about tractography data and show how our system
can be used to answer these questions efficiently.
@article{Sherbondy2005,
abstract = {Diffusion Tensor Imaging (DTI) is a magnetic resonance imaging method
that can be used to measure local information about the structure
of white matter within the human brain. Combining DTI data with
the computational methods of MR tractography, neuroscientists can
estimate the locations and sizes of nerve bundles (white matter
pathways) that course through the human brain. Neuroscientists have
used visualization techniques to better understand tractography
data, but they often struggle with the abundance and complexity
of the pathways. In this paper, we describe a novel set of interaction
techniques that make it easier to explore and interpret such pathways.
Specifically, our application allows neuroscientists to place and
interactively manipulate box or ellipsoid-shaped regions to selectively
display pathways that pass through specific anatomical areas. These
regions can be used in coordination with a simple and flexible query
language which allows for arbitrary combinations of these queries
using Boolean logic operators. A representation of the cortical
surface is provided for specifying queries of pathways that may
be relevant to gray matter structures and for displaying activation
information obtained from functional magnetic resonance imaging.
By precomputing the pathways and their statistical properties, we
obtain the speed necessary for interactive question-and-answer sessions
with brain researchers. We survey some questions that researchers
have been asking about tractography data and show how our system
can be used to answer these questions efficiently.},
added-at = {2007-01-10T11:43:56.000+0100},
author = {Sherbondy, A. and Akers, D. and Mackenzie, R. and Dougherty, R. and Wandell, B.},
biburl = {https://www.bibsonomy.org/bibtex/2c64bd65b1953fb347504ded28d9969c0/bmeyer},
description = {Diffusion Tensor Imaging (DTI)},
doi = {10.1109/TVCG.2005.59},
interhash = {6c687b4be7be1b5d7e1d70e3809c3ae3},
intrahash = {c64bd65b1953fb347504ded28d9969c0},
journal = {Visualization and Computer Graphics, IEEE Transactions on},
keywords = {Diffusion, Tensor DTI Imaging, Diffusion},
month = {July-Aug.},
number = 4,
owner = {bzfbmeye},
pages = {419--430},
timestamp = {2007-01-10T11:43:56.000+0100},
title = {Exploring connectivity of the brain's white matter with dynamic queries},
volume = 11,
year = 2005
}