Abstract

Hepatitis C virus (HCV) was discovered for the first time in 1989. It causes chronic liver disease. HCV is a plus-stranded RNA virus and belong to family Flaviviridae. About 3.3% (20 crore) of global population are infected due to HCV. Mostly it spread through contaminated syringes. In developed countries prevalence of HCV is low, e.g. Germany (0·6%), Canada (0·8%), Australia and France (1·1%). Low but little higher seroprevalence rate have been reported in USA (1·8%), Italy (2·2%) and Japan (1·5–2·3%). In developing countries including Pakistan its prevalence is high 0.5- 31.9%. Interferon based therapy are used for the treatment of HCVinfection.

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