Transcriptome analysis has been a key area of biological inquiry for decades. Over the years, research in the field has progressed from candidate gene-based detection of RNAs using Northern blotting to high-throughput expression profiling driven by the advent of microarrays. Next-generation sequencing technologies have revolutionized transcriptomics by providing opportunities for multidimensional examinations of cellular transcriptomes in which high-throughput expression data are obtained at a single-base resolution.
Description
Applications of new sequencing technologies for transcriptome analysis. - PubMed - NCBI
%0 Journal Article
%1 Morozova:2009:Annu-Rev-Genomics-Hum-Genet:19715439
%A Morozova, O
%A Hirst, M
%A Marra, M A
%D 2009
%J Annu Rev Genomics Hum Genet
%K PAYWALL gatc-biotech rna-seq
%P 135-151
%R 10.1146/annurev-genom-082908-145957
%T Applications of new sequencing technologies for transcriptome analysis
%U https://www.ncbi.nlm.nih.gov/pubmed/19715439
%V 10
%X Transcriptome analysis has been a key area of biological inquiry for decades. Over the years, research in the field has progressed from candidate gene-based detection of RNAs using Northern blotting to high-throughput expression profiling driven by the advent of microarrays. Next-generation sequencing technologies have revolutionized transcriptomics by providing opportunities for multidimensional examinations of cellular transcriptomes in which high-throughput expression data are obtained at a single-base resolution.
@article{Morozova:2009:Annu-Rev-Genomics-Hum-Genet:19715439,
abstract = {Transcriptome analysis has been a key area of biological inquiry for decades. Over the years, research in the field has progressed from candidate gene-based detection of RNAs using Northern blotting to high-throughput expression profiling driven by the advent of microarrays. Next-generation sequencing technologies have revolutionized transcriptomics by providing opportunities for multidimensional examinations of cellular transcriptomes in which high-throughput expression data are obtained at a single-base resolution.},
added-at = {2017-05-20T15:10:46.000+0200},
author = {Morozova, O and Hirst, M and Marra, M A},
biburl = {https://www.bibsonomy.org/bibtex/2e1b0a3fb21fb4ce4bee60c0ca539929a/marcsaric},
description = {Applications of new sequencing technologies for transcriptome analysis. - PubMed - NCBI},
doi = {10.1146/annurev-genom-082908-145957},
interhash = {9764b0c4de002f654d4878783d548888},
intrahash = {e1b0a3fb21fb4ce4bee60c0ca539929a},
journal = {Annu Rev Genomics Hum Genet},
keywords = {PAYWALL gatc-biotech rna-seq},
pages = {135-151},
pmid = {19715439},
timestamp = {2017-05-20T15:10:46.000+0200},
title = {Applications of new sequencing technologies for transcriptome analysis},
url = {https://www.ncbi.nlm.nih.gov/pubmed/19715439},
volume = 10,
year = 2009
}