Human leukocyte interferon at doses from 2 million units every two days to 3 million units daily was given to a 2-year-old boy for the treatment of recurrent juvenile laryngeal papilloma. After 7 months of treatment the child developed spastic diplegia, which persisted despite the discontinuation of interferon therapy. The clinical picture was consistent with an upper motor neuron lesion; no evidence of peripheral neuropathy was found.
%0 Journal Article
%1 Vesikari1988
%A Vesikari, T.
%A Nuutila, A.
%A Cantell, K.
%D 1988
%J Acta Paediatr Scand
%K Cerebral Palsy; Child, Preschool; Humans; Interferons; Laryngeal Neoplasms; Male; Neoplasm Recurrence, Local; Papilloma
%N 4
%P 619--622
%T Neurologic sequelae following interferon therapy of juvenile laryngeal papilloma.
%V 77
%X Human leukocyte interferon at doses from 2 million units every two days to 3 million units daily was given to a 2-year-old boy for the treatment of recurrent juvenile laryngeal papilloma. After 7 months of treatment the child developed spastic diplegia, which persisted despite the discontinuation of interferon therapy. The clinical picture was consistent with an upper motor neuron lesion; no evidence of peripheral neuropathy was found.
@article{Vesikari1988,
abstract = {Human leukocyte interferon at doses from 2 million units every two days to 3 million units daily was given to a 2-year-old boy for the treatment of recurrent juvenile laryngeal papilloma. After 7 months of treatment the child developed spastic diplegia, which persisted despite the discontinuation of interferon therapy. The clinical picture was consistent with an upper motor neuron lesion; no evidence of peripheral neuropathy was found.},
added-at = {2014-07-19T21:51:01.000+0200},
author = {Vesikari, T. and Nuutila, A. and Cantell, K.},
biburl = {https://www.bibsonomy.org/bibtex/2f0d7d54dffaa5f33a516ad6bfcbd5fae/ar0berts},
groups = {public},
interhash = {e749ebf945aa6777c36ce67874a091ef},
intrahash = {f0d7d54dffaa5f33a516ad6bfcbd5fae},
journal = {Acta Paediatr Scand},
keywords = {Cerebral Palsy; Child, Preschool; Humans; Interferons; Laryngeal Neoplasms; Male; Neoplasm Recurrence, Local; Papilloma},
month = Jul,
number = 4,
pages = {619--622},
pmid = {2455956},
timestamp = {2014-07-19T21:51:01.000+0200},
title = {Neurologic sequelae following interferon therapy of juvenile laryngeal papilloma.},
username = {ar0berts},
volume = 77,
year = 1988
}