For the successful treatment of pulmonary tuberculosis, drugs need to penetrate complex lung lesions and permeate the mycobacterial cell wall in order to reach their intracellular targets. However, most currently used anti-tuberculosis drugs were introduced into clinical use without considering the pharmacokinetic and pharmacodynamic properties
%0 Journal Article
%1 Dartois2014Path
%A Dartois, Veronique
%D 2014
%I Nature Publishing Group, a division of Macmillan Publishers Limited. All Rights Reserved.
%J Nat Rev Micro
%K combinatorial-therapy imaging tuberculosis
%N 3
%P 159--167
%R 10.1038/nrmicro3200
%T The path of anti-tuberculosis drugs: from blood to lesions to mycobacterial cells
%U http://dx.doi.org/10.1038/nrmicro3200
%V 12
%X For the successful treatment of pulmonary tuberculosis, drugs need to penetrate complex lung lesions and permeate the mycobacterial cell wall in order to reach their intracellular targets. However, most currently used anti-tuberculosis drugs were introduced into clinical use without considering the pharmacokinetic and pharmacodynamic properties
@article{Dartois2014Path,
abstract = {For the successful treatment of pulmonary tuberculosis, drugs need to penetrate complex lung lesions and permeate the mycobacterial cell wall in order to reach their intracellular targets. However, most currently used anti-tuberculosis drugs were introduced into clinical use without considering the pharmacokinetic and pharmacodynamic properties},
added-at = {2018-12-02T16:09:07.000+0100},
author = {Dartois, Veronique},
biburl = {https://www.bibsonomy.org/bibtex/2f6a07b0b4269eab85aa4af3a8dcc8a59/karthikraman},
citeulike-article-id = {13049944},
citeulike-linkout-0 = {http://dx.doi.org/10.1038/nrmicro3200},
citeulike-linkout-1 = {http://dx.doi.org/10.1038/nrmicro3200},
day = 03,
doi = {10.1038/nrmicro3200},
interhash = {a9b0c2b2589b2cb9bc6526690d64ad90},
intrahash = {f6a07b0b4269eab85aa4af3a8dcc8a59},
issn = {1740-1526},
journal = {Nat Rev Micro},
keywords = {combinatorial-therapy imaging tuberculosis},
month = mar,
number = 3,
pages = {159--167},
posted-at = {2014-03-18 06:58:11},
priority = {2},
publisher = {Nature Publishing Group, a division of Macmillan Publishers Limited. All Rights Reserved.},
timestamp = {2018-12-02T16:09:07.000+0100},
title = {The path of anti-tuberculosis drugs: from blood to lesions to mycobacterial cells},
url = {http://dx.doi.org/10.1038/nrmicro3200},
volume = 12,
year = 2014
}