%0 Generic %1 pandey_detection_2004 %A Pandey, S. %A White, M.H. %B The 26th Annual International Conference of the IEEE Engineering in Medicine and Biology Society %D 2004 %I IEEE %K Apertures, Microfluidics, Microstructure, Silicon, Voltage, aperture, cell counter, dielectrophoresis, electrical field microfluidics myown %P 1956--1959 %R 10.1109/IEMBS.2004.1403578 %T Detection of dielectrophoretic driven passage of single cells through micro-apertures in a silicon nitride membrane %U https://www.ece.iastate.edu/pandey/publications/ %V 1 %X Silicon (Si) microstructures are fabricated comprising a micro-aperture in a silicon nitride membrane connecting two microfluidic compartments. Dielectrophoretic forces are created on-chip, which guide the passage of single CHO cells through the microaperture. When a cell dielectrophoretically traverses the aperture, there is a decrease in the background ionic current. These current fluctuations are recorded under varying cell concentrations, micro-aperture sizes, and applied voltages. This work shows the feasibility of building silicon-based bioparticle detectors with nanoscale apertures for sensing the translocation of cells, proteins, and even single-stranded DNA.

@conference{pandey_detection_2004, abstract = {Silicon (Si) microstructures are fabricated comprising a micro-aperture in a silicon nitride membrane connecting two microfluidic compartments. Dielectrophoretic forces are created on-chip, which guide the passage of single CHO cells through the microaperture. When a cell dielectrophoretically traverses the aperture, there is a decrease in the background ionic current. These current fluctuations are recorded under varying cell concentrations, micro-aperture sizes, and applied voltages. This work shows the feasibility of building silicon-based bioparticle detectors with nanoscale apertures for sensing the translocation of cells, proteins, and even single-stranded DNA.}, added-at = {2022-07-12T23:10:12.000+0200}, author = {Pandey, S. and White, M.H.}, biburl = {https://www.bibsonomy.org/bibtex/2b2b22489d7c080a7d220e42e1c344cd2/spandey50}, booktitle = {The 26th {Annual} {International} {Conference} of the {IEEE} {Engineering} in {Medicine} and {Biology} {Society}}, doi = {10.1109/IEMBS.2004.1403578}, interhash = {4348c4a9175ef303c00578684835ab37}, intrahash = {b2b22489d7c080a7d220e42e1c344cd2}, keywords = {Apertures, Microfluidics, Microstructure, Silicon, Voltage, aperture, cell counter, dielectrophoresis, electrical field microfluidics myown}, language = {en}, month = sep, pages = {1956--1959}, publisher = {IEEE}, timestamp = {2023-02-23T21:17:40.000+0100}, title = {Detection of dielectrophoretic driven passage of single cells through micro-apertures in a silicon nitride membrane}, url = {https://www.ece.iastate.edu/pandey/publications/}, volume = 1, year = 2004 }