Synthesis, Characterization and Biological Studies of Metal Complexes Derived from 3–Hydroxyquinoxaline–2–Carboxaldehyde and 2–Aminobenzothiazole
P. Dharmapandian, J. Joseph, and J. Dharmaraja.
International Journal of Emerging Science and Engineering (IJESE) 5 (11): 10-14 (December 2018)

Novel metal complexes were synthesized by the condensation of 3–hydroxyquinoxaline–2–carboxaldehyde and 2–aminobenzothiazole. Using elemental analysis, IR, 1H–NMR, UV–Vis., molar conductance, magnetic moment and electrochemical studies, the ligands and its metal complexes were characterized. The magnetic moment and electronic spectral data evidenced that all the complexes exhibit square planar geometry. The metal complexes showed better antimicrobial screening than that of its free ligands. Using the cyclic voltammetry technique, the DNA binding behavior of complexes with CT DNA has been studied. The DNA binding constants revealed that intercalation binding mode for all metal complexes with DNA. Antibacterial screening of the ligand and its complexes reveal that all the complexes show higher activities than the ligand.
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