%0 Journal Article %1 Wang2012166 %A Wang, Limei %A Wang, Shuqi %A Yang, Shuang %A Guo, Xiaojiang %A Lou, Hongxiang %A Ren, Dongmei %D 2012 %J Phytochemistry %K Dracocephalum heterophyllum phenolics phdDraco %N 0 %P 166 - 171 %R 10.1016/j.phytochem.2012.06.021 %T Phenolic alkaloids from the aerial parts of Dracocephalum heterophyllum %U http://www.sciencedirect.com/science/article/pii/S0031942212002993 %V 82 %X Chemical examination of aerial parts of Dracocephalum heterophyllum resulted in isolation of phenolic alkaloids, including two flavonoidal alkaloids, drahebephins A and B, one imidazole alkaloid with a phenolic substituent, drahebenine, together with 15 other known compounds. Their structures were established by extensive spectroscopic data analyses. Due to the stereogenic center in the pyrrolidin-2-one ring, the flavonoidal alkaloids are chiral, although they were isolated as racemates. The enantiomers were separated by \HPLC\ using a chiral phase and stereochemically characterized by circular dichroism (CD) spectroscopy. The structure of compound drahebenine was established by X-ray crystallography.

@article{Wang2012166, abstract = {Chemical examination of aerial parts of Dracocephalum heterophyllum resulted in isolation of phenolic alkaloids, including two flavonoidal alkaloids, drahebephins A and B, one imidazole alkaloid with a phenolic substituent, drahebenine, together with 15 other known compounds. Their structures were established by extensive spectroscopic data analyses. Due to the stereogenic center in the pyrrolidin-2-one ring, the flavonoidal alkaloids are chiral, although they were isolated as racemates. The enantiomers were separated by \{HPLC\} using a chiral phase and stereochemically characterized by circular dichroism (CD) spectroscopy. The structure of compound drahebenine was established by X-ray crystallography. }, added-at = {2013-09-18T20:09:56.000+0200}, author = {Wang, Limei and Wang, Shuqi and Yang, Shuang and Guo, Xiaojiang and Lou, Hongxiang and Ren, Dongmei}, biburl = {https://www.bibsonomy.org/bibtex/2c585023c4aa60c28188f6a2e5717a8ed/drgirasol}, description = {Phenolic alkaloids from the aerial parts of Dracocephalum heterophyllum}, doi = {10.1016/j.phytochem.2012.06.021}, interhash = {553c1ca5ab9a8b1a17c7aa153e27ba4c}, intrahash = {c585023c4aa60c28188f6a2e5717a8ed}, issn = {0031-9422}, journal = {Phytochemistry }, keywords = {Dracocephalum heterophyllum phenolics phdDraco}, number = 0, pages = {166 - 171}, timestamp = {2013-09-19T12:27:04.000+0200}, title = {Phenolic alkaloids from the aerial parts of Dracocephalum heterophyllum }, url = {http://www.sciencedirect.com/science/article/pii/S0031942212002993}, volume = 82, year = 2012 }