Article,
Altered cardiac myocyte Ca regulation in heart failure.
Physiology (Bethesda), (December 2006)
DOI: 10.1152/physiol.00019.2006
Abstract
Ca is critical in both the electrical and mechanical properties of
cardiac myocytes, and much is known about ionic currents and the
normal excitation-contraction coupling process. In heart failure,
there are significant alterations in how myocyte Ca is regulated,
and these alterations are critical in dictating both contractile
dysfunction and certain cardiac arrhythmias that are characteristic
of heart failure.
