%0 Journal Article %1 giovannoni2005genome %A Giovannoni, Stephen J. %A Tripp, H. James %A Givan, Scott %A Podar, Mircea %A Vergin, Kevin L. %A Baptista, Damon %A Bibbs, Lisa %A Eads, Jonathan %A Richardson, Toby H. %A Noordewier, Michiel %A Rappé, Michael S. %A Short, Jay M. %A Carrington, James C. %A Mathur, Eric J. %D 2005 %J Science %K Pelagibacter dynamical_systems mutation_selection_balance %N 5738 %P 1242-1245 %R 10.1126/science.1114057 %T Genome Streamlining in a Cosmopolitan Oceanic Bacterium %U http://www.sciencemag.org/content/309/5738/1242.abstract %V 309 %X The SAR11 clade consists of very small, heterotrophic marine α-proteobacteria that are found throughout the oceans, where they account for about 25% of all microbial cells. Pelagibacter ubique, the first cultured member of this clade, has the smallest genome and encodes the smallest number of predicted open reading frames known for a free-living microorganism. In contrast to parasitic bacteria and archaea with small genomes, P. ubique has complete biosynthetic pathways for all 20 amino acids and all but a few cofactors. P. ubique has no pseudogenes, introns, transposons, extrachromosomal elements, or inteins; few paralogs; and the shortest intergenic spacers yet observed for any cell.

@article{giovannoni2005genome, abstract = {The SAR11 clade consists of very small, heterotrophic marine α-proteobacteria that are found throughout the oceans, where they account for about 25% of all microbial cells. Pelagibacter ubique, the first cultured member of this clade, has the smallest genome and encodes the smallest number of predicted open reading frames known for a free-living microorganism. In contrast to parasitic bacteria and archaea with small genomes, P. ubique has complete biosynthetic pathways for all 20 amino acids and all but a few cofactors. P. ubique has no pseudogenes, introns, transposons, extrachromosomal elements, or inteins; few paralogs; and the shortest intergenic spacers yet observed for any cell.}, added-at = {2015-03-28T21:59:16.000+0100}, author = {Giovannoni, Stephen J. and Tripp, H. James and Givan, Scott and Podar, Mircea and Vergin, Kevin L. and Baptista, Damon and Bibbs, Lisa and Eads, Jonathan and Richardson, Toby H. and Noordewier, Michiel and Rappé, Michael S. and Short, Jay M. and Carrington, James C. and Mathur, Eric J.}, biburl = {https://www.bibsonomy.org/bibtex/2ec434e627a9cd38f7a9cc5183db0cf9a/peter.ralph}, doi = {10.1126/science.1114057}, eprint = {http://www.sciencemag.org/content/309/5738/1242.full.pdf}, interhash = {6d717486c0ffdd82487fd10499e6b0dd}, intrahash = {ec434e627a9cd38f7a9cc5183db0cf9a}, journal = {Science}, keywords = {Pelagibacter dynamical_systems mutation_selection_balance}, number = 5738, pages = {1242-1245}, timestamp = {2015-03-28T21:59:16.000+0100}, title = {Genome Streamlining in a Cosmopolitan Oceanic Bacterium}, url = {http://www.sciencemag.org/content/309/5738/1242.abstract}, volume = 309, year = 2005 }