Article,

Mortality and morbidity in extremely preterm infants (22 to 26 weeks of gestation): Austria 1999-2001.

, , , , , , , , , , , , , , , , , , , and .
Wien Klin Wochenschr, 117 (21-22): 740--746 (November 2005)
DOI: 10.1007/s00508-005-0468-y

Abstract

OBJECTIVE: The aim of this retrospective study was to analyze the mortality and morbidity for extremely preterm infants with a gestational age from 22 to 26 weeks. All infants were born in Austria during the years 1999-2001. METHODS: Data were collected from 16 neonatal intensive care units in Austria. Main outcome criteria were mortality, the rates of chronic lung disease (CLD) and severe retinopathy of prematurity (ROP, stage > or =3) to determine the short-term outcome; the rate of cerebral palsy (CP) at the corrected age of twelve months to assess the long-term outcome. RESULTS: Overall, 796 preterm infants with a gestational age less than 27 weeks were born in Austria and 581 (73\%) were registered as live-born infants. Of those live born, 508 (87\%) were analyzed. The mortality rates were 83\%, 76\%, 43\%, 26\% and 13\% for 22, 23, 24, 25 and 26 weeks' gestation, respectively. The rates of CLD were 33\% (22 weeks), 36\% (23 weeks), 42\% (24 weeks), 31\% (25 weeks) and 22\% (26 weeks). The rates of ROP of stage > or =3 were 0\% (22 weeks), 29\% (23 weeks), 23\% (24 weeks), 18\% (25 weeks) and 10\% (26 weeks). The rates of CP at the corrected age of 12 months were 33\%, 50\%, 33\%, 26\% and 25\% for 22, 23, 24, 25 and 26 weeks' gestation, respectively. CONCLUSIONS: The results of this national study are in accordance with the international literature: mortality and morbidity increased with decreasing gestational age.

Tags

Users

  • @ar0berts

Comments and Reviews