%0 Journal Article %1 Matsuda2002 %A Matsuda, Yoshio %A Kouno, Satoshi %D 2002 %J Fetal Diagn Ther %K Amniocentesis; Cerebral Palsy; Cohort Studies; Female; Fetofetal Transfusion; Humans; Hydrops Fetalis; Infant, Newborn; Oligohydramnios; Polyhydramnios; Pregnancy; Pregnancy Outcome; Prognosis; Retrospective Studies %N 5 %P 268--271 %T Fetal and neonatal outcomes in twin oligohydramnios-polyhydramnios sequence including cerebral palsy. %V 17 %X OBJECTIVE: The purpose of this study was to review consecutive pregnancies complicated by twin oligohydramnios-polyhydramnios sequence (TOPS) and to clarify the probable factors influencing the perinatal outcomes. METHODS: Twenty-five pregnancies with a diagnosis of TOPS were treated with and without amniocentesis. A poor perinatal outcome was defined when either perinatal mortality or cerebral palsy was observed. RESULTS: The mean gestational age at the time of diagnosis and of delivery was 27.8 (range 21-34) and 30.7 (range 23-35) weeks, respectively. Tocolytic therapy and therapeutic amniocentesis were done in 16 (64\%) and 13 (52\%) cases. Hydrops fetalis was present in 10 cases. The survival rate was 72\%, and cerebral palsy was diagnosed in 8 of 36 infants (22\%). The poor prognostic factors were gestational age at delivery (<30 weeks) and presence of symptomatic preterm labor and hydrops fetalis. Therapeutic amniocentesis did not influence the perinatal outcome. CONCLUSIONS: In this observational study, the long-term as well as the short-term perinatal outcome of pregnancy with TOPS seems to be poor. In addition, therapeutic amniocentesis in TOPS does not appear to affect fetal and neonatal outcomes.

@article{Matsuda2002, abstract = {OBJECTIVE: The purpose of this study was to review consecutive pregnancies complicated by twin oligohydramnios-polyhydramnios sequence (TOPS) and to clarify the probable factors influencing the perinatal outcomes. METHODS: Twenty-five pregnancies with a diagnosis of TOPS were treated with and without amniocentesis. A poor perinatal outcome was defined when either perinatal mortality or cerebral palsy was observed. RESULTS: The mean gestational age at the time of diagnosis and of delivery was 27.8 (range 21-34) and 30.7 (range 23-35) weeks, respectively. Tocolytic therapy and therapeutic amniocentesis were done in 16 (64\%) and 13 (52\%) cases. Hydrops fetalis was present in 10 cases. The survival rate was 72\%, and cerebral palsy was diagnosed in 8 of 36 infants (22\%). The poor prognostic factors were gestational age at delivery (<30 weeks) and presence of symptomatic preterm labor and hydrops fetalis. Therapeutic amniocentesis did not influence the perinatal outcome. CONCLUSIONS: In this observational study, the long-term as well as the short-term perinatal outcome of pregnancy with TOPS seems to be poor. In addition, therapeutic amniocentesis in TOPS does not appear to affect fetal and neonatal outcomes.}, added-at = {2014-07-19T20:46:04.000+0200}, author = {Matsuda, Yoshio and Kouno, Satoshi}, biburl = {https://www.bibsonomy.org/bibtex/22934c86ae39def5551681cec892d8ad1/ar0berts}, groups = {public}, interhash = {85855737cdf65a2b775c86a8120230c3}, intrahash = {2934c86ae39def5551681cec892d8ad1}, journal = {Fetal Diagn Ther}, keywords = {Amniocentesis; Cerebral Palsy; Cohort Studies; Female; Fetofetal Transfusion; Humans; Hydrops Fetalis; Infant, Newborn; Oligohydramnios; Polyhydramnios; Pregnancy; Pregnancy Outcome; Prognosis; Retrospective Studies}, number = 5, pages = {268--271}, pii = {fdt17268}, pmid = {12169809}, timestamp = {2014-07-19T20:46:04.000+0200}, title = {Fetal and neonatal outcomes in twin oligohydramnios-polyhydramnios sequence including cerebral palsy.}, username = {ar0berts}, volume = 17, year = 2002 }