Inproceedings,

The Two-Locus Ancestral Graph

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Selected Proceedings of the Sheffield Symposium on Applied Probability, volume 18 of Lecture Notes--Monograph Series, page pp. 100-117. Hayward, CA, Institute of Mathematical Statistics, (1991)

Abstract

In a population genetics two-locus model with recombination an offspring has either a single parent gene, or is a recombinant from two parent genes. The number of ancestors, backward in time, of a sample of genes can thus decrease or increase and is found to be a birth and death process. Instead of a one-locus ancestral tree the ancestral paths of a sample of gene pairs are described by a graph with leaves as the sample genes and an eventual common ancestor where all paths from the leaves lead. In this paper properties of the two-locus ancestral graph and the two marginal ancestral trees are studied.

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