%0 Journal Article %1 Maruyama:1972:Ann-Hum-Genet:5073689 %A Maruyama, T %D 1972 %J Ann Hum Genet %K deleterious_alleles recessive_alleles spatial_structure stepping_stone_models %N 4 %P 425-432 %R 10.1111/j.1469-1809.1957.tb01867.x %T Distribution of gene frequencies in a geographically structured population. II. Distribution of deleterious genes and of lethal genes %U http://onlinelibrary.wiley.com/doi/10.1111/j.1469-1809.1957.tb01867.x/abstract %V 35 %X I n my previous paper, I dealt with the neutral and nearly neutral genes in a geographically structured population and obtained approximation formulae for the distribution of gene fre- quencies in the entire population and in a local population (Maruyama, 1972). I n this paper I will discuss the fate of the deleterious genes which arise in geographicallystructured populations. As in the previous paper, I will use two models of population structure : the stepping-stone model and the continuous model. I n Q 2 of this paper the assumption is made that a colony of a one- dimensional population exchanges its members with each of its two neighbouring colonies at the rate ijm and a colony of a two-dimensional population exchanges its members with each of its four neighbouring colonies at the rate &m,and that the migration in a continuous population is isotropical and the variance of the migration distance is &'. These assumptions are not essential but made for simplicity. For further details of the models, see Maruyama (1970, 1971).

@article{Maruyama:1972:Ann-Hum-Genet:5073689, abstract = { I n my previous paper, I dealt with the neutral and nearly neutral genes in a geographically structured population and obtained approximation formulae for the distribution of gene fre- quencies in the entire population and in a local population (Maruyama, 1972). I n this paper I will discuss the fate of the deleterious genes which arise in geographicallystructured populations. As in the previous paper, I will use two models of population structure : the stepping-stone model and the continuous model. I n Q 2 of this paper the assumption is made that a colony of a one- dimensional population exchanges its members with each of its two neighbouring colonies at the rate ijm and a colony of a two-dimensional population exchanges its members with each of its four neighbouring colonies at the rate &m,and that the migration in a continuous population is isotropical and the variance of the migration distance is &'. These assumptions are not essential but made for simplicity. For further details of the models, see Maruyama (1970, 1971). }, added-at = {2010-09-02T03:54:37.000+0200}, author = {Maruyama, T}, biburl = {https://www.bibsonomy.org/bibtex/201a4321b6a21b761d9318e344534d43b/peter.ralph}, description = {Distribution of gene frequencies in a geographical... [Ann Hum Genet. 1972] - PubMed result}, doi = {10.1111/j.1469-1809.1957.tb01867.x}, interhash = {989668ffa184fa51b8ad25b4926adacd}, intrahash = {01a4321b6a21b761d9318e344534d43b}, journal = {Ann Hum Genet}, keywords = {deleterious_alleles recessive_alleles spatial_structure stepping_stone_models}, month = apr, number = 4, pages = {425-432}, pmid = {5073689}, timestamp = {2010-09-02T03:54:38.000+0200}, title = {Distribution of gene frequencies in a geographically structured population. {II.} {Distribution} of deleterious genes and of lethal genes}, url = {http://onlinelibrary.wiley.com/doi/10.1111/j.1469-1809.1957.tb01867.x/abstract}, volume = 35, year = 1972 }