Bronchopulmonary dysplasia: a longitudinal study of 20 cases.
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Helv Paediatr Acta 42 (4): 263--271 (1987)

Of 20 patients with bronchopulmonary dysplasia (BPD), 17 survived (85\%) and were followed prospectively up to one year post-term. Lower respiratory tract infections occurred in 12 patients (70.5\%), and in 7 (41\%) at least one hospital admission was required. At one year post-term follow-up, 9 patient (52.9\%) continued to present respiratory symptoms, and 5 out of 13 (38.4\%) radiographic changes. Six cases (35\%) presented chronic cor pulmonale. Only 6 children (35\%) showed normal growth, while the others showed deficits in one or more growth parameters. Cerebral palsy occurred in 41\% of the children; 3 cases of severe tetraparesis and 4 of moderately severe palsy (hemiparesis or diplegia). Developmental quotient (DQ) was less than 70 in 6 cases (35\%), from 70-90 in 4 (23.5\%), and greater than 90 in 7 (41\%). The severe neurodevelopmental outcomes were significantly correlated with the presence of important neonatal cerebral pathology (3-4 degrees IVH or periventricular leukomalacia). Retinopathy due to prematurity was diagnosed in 7 patients (41\%), and in 5 it progressed to retrolental fibroplasia. Ten cases (58.8\%) showed strabism, of which 8 had previous eye background involvement. Hearing deficit was not detected in any patient. Esthetic and functional sequelae consisted of scalp eschar (3 cases), post-thoracotomy scar (1 case), pleural drainage scars (3 cases), nasal deformity due to prolonged intubation (1 case), laryngeal stenosis (1 case), and post-tracheostomy stenosis (1 case).(ABSTRACT TRUNCATED AT 250 WORDS)
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