Ocular significance of intraventricular haemorrhage in premature infants.
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Br J Ophthalmol 85 (3): 357--359 (March 2001)

AIM: To document ocular outcome in premature infants with intraventricular haemorrhages (IVH). METHODS: 68 preterm infants with IVH were examined. RESULTS: Mean gestational age was 28.1 weeks (range 24-35). Mean birth weight was 1045.9 g (630-2240). Mean follow up was 54.6 months (6-150). IVH is graded from 1 to 4 based on the severity of haemorrhages. The incidence of ocular abnormalities was compared between low grade IVH (grade 1 and 2) and high grade IVH (grade 3 and 4). Of the 68 infants with IVH, ROP occurred in 33 infants (48.5\%); 13 (43.3\%) had low grade IVH; 20 (52.6\%) had high grade IVH. Strabismus developed in 30 infants (44.1\%); 14 (46.6\%) had low grade IVH; 16 (42.1\%) had high grade IVH. Infants with high grade IVH were at significant greater risk than infants with low grade IVH for the development of optic atrophy (31.5\% v 16.6\%), hydrocephalus (57.8\% v 10\%). CONCLUSION: This study highlights the serious significance of all grades of IVH with the higher incidence of optic atrophy and hydrocephalus with high grade IVH.
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