SARS-CoV-2 infection displays immense inter-individual clinical variability, ranging from silent infection to lethal disease. The role of human genetics in determining clinical response to the virus remains unclear. Studies of outliers – individuals remaining uninfected despite viral exposure and healthy young patients with life-threatening disease – presents a unique opportunity to reveal human genetic determinants of infection and disease.
Description
A global effort to define the human genetics of protective immunity to SARS-CoV-2 infection - ScienceDirect
%0 Journal Article
%1 CASANOVA2020
%A Casanova, Jean-Laurent
%A Su, Helen C. on behalf of the COVID Human Genetic Effort
%D 2020
%J Cell
%K SARS-Cov-2
%R https://doi.org/10.1016/j.cell.2020.05.016
%T A global effort to define the human genetics of protective immunity to SARS-CoV-2 infection
%U http://www.sciencedirect.com/science/article/pii/S0092867420306115
%X SARS-CoV-2 infection displays immense inter-individual clinical variability, ranging from silent infection to lethal disease. The role of human genetics in determining clinical response to the virus remains unclear. Studies of outliers – individuals remaining uninfected despite viral exposure and healthy young patients with life-threatening disease – presents a unique opportunity to reveal human genetic determinants of infection and disease.
@article{CASANOVA2020,
abstract = {SARS-CoV-2 infection displays immense inter-individual clinical variability, ranging from silent infection to lethal disease. The role of human genetics in determining clinical response to the virus remains unclear. Studies of outliers – individuals remaining uninfected despite viral exposure and healthy young patients with life-threatening disease – presents a unique opportunity to reveal human genetic determinants of infection and disease.},
added-at = {2020-05-17T14:15:57.000+0200},
author = {Casanova, Jean-Laurent and Su, Helen C. on behalf of the COVID Human Genetic Effort},
biburl = {https://www.bibsonomy.org/bibtex/2ac57beac590560089863efac46fc3596/lkanth},
description = {A global effort to define the human genetics of protective immunity to SARS-CoV-2 infection - ScienceDirect},
doi = {https://doi.org/10.1016/j.cell.2020.05.016},
interhash = {7d1f08b8caa2874c8affb9186921bc28},
intrahash = {ac57beac590560089863efac46fc3596},
issn = {0092-8674},
journal = {Cell},
keywords = {SARS-Cov-2},
timestamp = {2020-05-17T14:15:57.000+0200},
title = {A global effort to define the human genetics of protective immunity to SARS-CoV-2 infection},
url = {http://www.sciencedirect.com/science/article/pii/S0092867420306115},
year = 2020
}