This review covers classical and modern structural modifications of the alkaloid, the more recent (since 2007) syntheses of cytisine and analogues, and the pharmacology of these compounds, with emphasis on their interactions with nicotinic receptors. 89 references are cited.
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%0 Journal Article
%1 RN68
%A Perez, E.G.
%A Mendez-Galvez, C.
%A Cassels, B.K.
%D 2012
%J Natural Product Reports
%K agonists crystal-structure, diastereoselective discriminative dqcauchile evaluation, functionalization, high-affinity, in-vivo, ligands nachr nitrogen partial pharmacological properties, smoking-cessation, stimulus substitution, varenicline,
%N 5
%P 555-567
%R 10.1039/c2np00100d
%T Cytisine: A Natural Product Lead for the Development of Drugs Acting at Nicotinic Acetylcholine Receptors
%U /brokenurl#<Go to ISI>://WOS:000302635800003
%V 29
%X This review covers classical and modern structural modifications of the alkaloid, the more recent (since 2007) syntheses of cytisine and analogues, and the pharmacology of these compounds, with emphasis on their interactions with nicotinic receptors. 89 references are cited.
@article{RN68,
abstract = {This review covers classical and modern structural modifications of the alkaloid, the more recent (since 2007) syntheses of cytisine and analogues, and the pharmacology of these compounds, with emphasis on their interactions with nicotinic receptors. 89 references are cited.},
added-at = {2019-12-04T03:57:35.000+0100},
author = {Perez, E.G. and Mendez-Galvez, C. and Cassels, B.K.},
biburl = {https://www.bibsonomy.org/bibtex/2ed9bdb6c4489fd33337b83ff04b3113e/dqcauchile},
doi = {10.1039/c2np00100d},
interhash = {e56043ad49afce450decd66b181bc07a},
intrahash = {ed9bdb6c4489fd33337b83ff04b3113e},
issn = {0265-0568},
journal = {Natural Product Reports},
keywords = {agonists crystal-structure, diastereoselective discriminative dqcauchile evaluation, functionalization, high-affinity, in-vivo, ligands nachr nitrogen partial pharmacological properties, smoking-cessation, stimulus substitution, varenicline,},
number = 5,
pages = {555-567},
timestamp = {2019-12-04T03:58:17.000+0100},
title = {Cytisine: A Natural Product Lead for the Development of Drugs Acting at Nicotinic Acetylcholine Receptors},
type = {Journal Article},
url = {/brokenurl#<Go to ISI>://WOS:000302635800003},
volume = 29,
year = 2012
}