%0 Journal Article %1 Fu2009 %A bin Fu, Wen %A Fan, Li %A ping Zhu, Xiao %A He, Qing %A Wang, Ling %A xing Zhuang, Li %A sheng Liu, Yuan %A zhi Tang, Chun %A wen Li, Ying %A rong Meng, Chang %A lai Zhang, Hong %A Yan, Jie %D 2009 %J J Tradit Chin Med %K Acupuncture Adult; Aged Agents, Antidepressive Depressive Disorder, Female; Fluoxetine, Humans; Liver, Male; Middle Second-Generation, Therapy, diagnosis/drug drug effects/metabolism; methods; therapeutic therapy/therapy; use; %N 2 %P 83--86 %T Depressive neurosis treated by acupuncture for regulating the liver--a report of 176 cases. %V 29 %X To observe therapeutic effect of acupuncture for regulating the liver on depressive neurosis.In a multi-center randomized controlled trial, 440 patients were divided into 3 groups: Acupuncture group for regulating the liver (Acup., 176 cases) was treated by acupuncture at Siguan Points, i.e., bilateral Hegu (LI 4) and Taichong (LR 3), Baihui (GV 20) and Yintang (EX-HN3) plus ear-acupuncture, Prozac group (P., 176 cases) by oral administration of Prozac, and Non-acupoint needling group (NAN, 88 cases) by acupuncture at non-acupoints as acupuncture placebo. Self-rating Depression Scale (SDS) was examined before treatment, and one month, two and three months after treatment respectively to evaluate therapeutic effect, and Rating Scale for Side Effects (SERS) was used to evaluate the safety.After one month of treatment, SDS scores in Acup. Group were significantly lower than that in P. Group (P < 0.05) and than that in NAN Group (P < 0.01), and SDS scores in P. Group were lower than that in NAN Group (P < 0.05), showing the SDS scores in Acup. Group < P. Group < NAN Group. After 2 months of treatment, SDS scores in Acup. Group were also significantly lower than that in P. Group (P < 0.01) and than that in NAN Group (P < 0.01), and SDS scores in P. Group were also lower than that in NAN Group (P < 0.05), showing the SDS scores in Acup. Group <P. Group <NAN Group. After 3 months of treatment, SDS scores in Acup. Group were also significantly lower than that in P. Group (P < 0.01) and than that in NAN Group (P < 0.01), and SDS scores in P. Group were also lower than that in NAN Group (P < 0.01), showing the SDS score in Acup. Group < P. Group < NAN Group. After treatment, SERS scores were 0.16 +/- 0.95, 6.51 +/- 5.09 and 0.23 +/- 1.36 in Acup. Group, P. Group and NAN Group respectively. A significant difference existed between Acup. Group and P. Group (P < 0.05), but no significant difference between Acup. Group and NAN Group (P > 0.05), showing the SERS scores in Acup. Group < NAN Group < P. Group. No side effect was found in Acup. and NAN groups.The therapeutic effect of acupuncture on depressive neurosis is better than or similar to that of Prozac but with less side effect.

@article{Fu2009, abstract = {To observe therapeutic effect of acupuncture for regulating the liver on depressive neurosis.In a multi-center randomized controlled trial, 440 patients were divided into 3 groups: Acupuncture group for regulating the liver (Acup., 176 cases) was treated by acupuncture at Siguan Points, i.e., bilateral Hegu (LI 4) and Taichong (LR 3), Baihui (GV 20) and Yintang (EX-HN3) plus ear-acupuncture, Prozac group (P., 176 cases) by oral administration of Prozac, and Non-acupoint needling group (NAN, 88 cases) by acupuncture at non-acupoints as acupuncture placebo. Self-rating Depression Scale (SDS) was examined before treatment, and one month, two and three months after treatment respectively to evaluate therapeutic effect, and Rating Scale for Side Effects (SERS) was used to evaluate the safety.After one month of treatment, SDS scores in Acup. Group were significantly lower than that in P. Group (P < 0.05) and than that in NAN Group (P < 0.01), and SDS scores in P. Group were lower than that in NAN Group (P < 0.05), showing the SDS scores in Acup. Group < P. Group < NAN Group. After 2 months of treatment, SDS scores in Acup. Group were also significantly lower than that in P. Group (P < 0.01) and than that in NAN Group (P < 0.01), and SDS scores in P. Group were also lower than that in NAN Group (P < 0.05), showing the SDS scores in Acup. Group <P. Group <NAN Group. After 3 months of treatment, SDS scores in Acup. Group were also significantly lower than that in P. Group (P < 0.01) and than that in NAN Group (P < 0.01), and SDS scores in P. Group were also lower than that in NAN Group (P < 0.01), showing the SDS score in Acup. Group < P. Group < NAN Group. After treatment, SERS scores were 0.16 +/- 0.95, 6.51 +/- 5.09 and 0.23 +/- 1.36 in Acup. Group, P. Group and NAN Group respectively. A significant difference existed between Acup. Group and P. Group (P < 0.05), but no significant difference between Acup. Group and NAN Group (P > 0.05), showing the SERS scores in Acup. Group < NAN Group < P. Group. No side effect was found in Acup. and NAN groups.The therapeutic effect of acupuncture on depressive neurosis is better than or similar to that of Prozac but with less side effect.}, added-at = {2012-03-25T23:23:14.000+0200}, author = {bin Fu, Wen and Fan, Li and ping Zhu, Xiao and He, Qing and Wang, Ling and xing Zhuang, Li and sheng Liu, Yuan and zhi Tang, Chun and wen Li, Ying and rong Meng, Chang and lai Zhang, Hong and Yan, Jie}, biburl = {https://www.bibsonomy.org/bibtex/272992fe65ff11c9114cc341bfa19e102/antmoreira}, institution = {Guangdong Hospital of TCM, Guangzhou 510120, China.}, interhash = {f33efed5eae9289688bdab3530687274}, intrahash = {72992fe65ff11c9114cc341bfa19e102}, journal = {J Tradit Chin Med}, keywords = {Acupuncture Adult; Aged Agents, Antidepressive Depressive Disorder, Female; Fluoxetine, Humans; Liver, Male; Middle Second-Generation, Therapy, diagnosis/drug drug effects/metabolism; methods; therapeutic therapy/therapy; use;}, language = {eng}, medline-pst = {ppublish}, month = Jun, number = 2, pages = {83--86}, pmid = {19663089}, timestamp = {2012-03-25T23:23:15.000+0200}, title = {Depressive neurosis treated by acupuncture for regulating the liver--a report of 176 cases.}, volume = 29, year = 2009 }