Artikel,

Complex network analysis in microbial systems: theory and examples.

, und .
Methods in molecular biology (Clifton, N.J.), (2012)
DOI: 10.1007/978-1-61779-827-6\_19

Zusammenfassung

An essential idea in the area of Systems Biology is that a good understanding of interactions between components is crucial for developing deep knowledge of the functioning of the system as a whole. Network analysis is an approach uniquely suited to uncover patterns and organizing principles in a wide variety of complex systems. In this chapter, we will give a detailed description of central network concepts and their algorithmic implementation, and demonstrate how they may be applied on two biological networks: the protein-interaction network of Mus musculus and the reconstructed genome-scale metabolic network of the bacterium Yersinia pestis.

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