%0 Journal Article %1 baharian2016great %A Baharian, Soheil %A Barakatt, Maxime %A Gignoux, Christopher R. %A Shringarpure, Suyash %A Errington, Jacob %A Blot, William J. %A Bustamante, Carlos D. %A Kenny, Eimear E. %A Williams, Scott M. %A Aldrich, Melinda C. %A Gravel, Simon %D 2016 %I Public Library of Science %J PLOS Genetics %K IBD demographic_inference %N 5 %P 1-27 %R 10.1371/journal.pgen.1006059 %T The Great Migration and African-American Genomic Diversity %U https://doi.org/10.1371/journal.pgen.1006059 %V 12 %X Author Summary Genetic studies of African-Americans identify functional variants, elucidate historical and genealogical mysteries, and reveal basic biology. However, African-Americans have been under-represented in genetic studies, and relatively little is known about nation-wide patterns of genomic diversity in the population. Here, we study African-American genomic diversity using genotype data from nationally and regionally representative cohorts. Access to these unique cohorts allows us to clarify the role of population structure, admixture, and recent massive migrations in shaping African-American genomic diversity and sheds new light on the genetic history of this population.

@article{baharian2016great, abstract = {Author Summary Genetic studies of African-Americans identify functional variants, elucidate historical and genealogical mysteries, and reveal basic biology. However, African-Americans have been under-represented in genetic studies, and relatively little is known about nation-wide patterns of genomic diversity in the population. Here, we study African-American genomic diversity using genotype data from nationally and regionally representative cohorts. Access to these unique cohorts allows us to clarify the role of population structure, admixture, and recent massive migrations in shaping African-American genomic diversity and sheds new light on the genetic history of this population.}, added-at = {2018-10-01T08:47:57.000+0200}, author = {Baharian, Soheil and Barakatt, Maxime and Gignoux, Christopher R. and Shringarpure, Suyash and Errington, Jacob and Blot, William J. and Bustamante, Carlos D. and Kenny, Eimear E. and Williams, Scott M. and Aldrich, Melinda C. and Gravel, Simon}, biburl = {https://www.bibsonomy.org/bibtex/2bd31dc0856b70ceb4b3106b5d24b2a20/peter.ralph}, doi = {10.1371/journal.pgen.1006059}, interhash = {f75c984b078e81fd918bb015d0ea9777}, intrahash = {bd31dc0856b70ceb4b3106b5d24b2a20}, journal = {PLOS Genetics}, keywords = {IBD demographic_inference}, month = {05}, number = 5, pages = {1-27}, publisher = {Public Library of Science}, timestamp = {2018-10-01T08:47:57.000+0200}, title = {The Great Migration and African-American Genomic Diversity}, url = {https://doi.org/10.1371/journal.pgen.1006059}, volume = 12, year = 2016 }