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A SERCA2 pump with an increased Ca2+ affinity can lead to severe cardiac hypertrophy, stress intolerance and reduced life span.

, , , , , , , , , , , and . J Mol Cell Cardiol, 41 (2): 308--317 (August 2006)
DOI: 10.1016/j.yjmcc.2006.05.014

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