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Interferon-beta expression and type I interferon receptor signaling of hepatocytes prevent hepatic necrosis and virus dissemination in Coxsackievirus B3-infected mice

W. Koestner, J. Spanier, T. Klause, P. Tegtmeyer, J. Becker, V. Herder, K. Borst, D. Todt, S. Lienenklaus, I. Gerhauser, C. Detje, R. Geffers, M. Langereis, F. Vondran, Q. Yuan, F. van Kuppeveld, M. Ott, P. Staeheli, E. Steinmann, W. Baumgartner, F. Wacker, U. Kalinke, T. Klause, P. Tegtmeyer, J. Becker, V. Herder, K. Borst, D. Todt, S. Lienenklaus, I. Gerhauser, C. Detje, R. Geffers, M. Langereis, F. Vondran, Q. Yuan, F. van Kuppeveld, M. Ott, P. Staeheli, E. Steinmann, W. Baumgärtner, F. Wacker, and U. Kalinke. PLOS Pathog, 14 (8): 1-23 (August 2018)

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Control of Nipah Virus infection in mice by the host adaptors mitochondrial antiviral signaling protein (MAVS) and Myeloid differentiation primary response 88 (MyD88)M. Iampietro, N. Aurine, K. Dhondt, C. Dumont, R. Pelissier, J. Spanier, A. Vallve, H. Raoul, U. Kalinke, and B. Horvat. J Infect Dis, 221 ((Supplement_4)): S401-S406 (December 2020)Type I Interferon Receptor Signaling of Neurons and Astrocytes Regulates Microglia Activation during Viral EncephalitisC. Chhatbar, C. Detje, E. Grabski, K. Borst, J. Spanier, L. Ghita, D. Elliott, M. Jordao, N. Mueller, J. Sutton and 7 other author(s). Cell Rep, 25 (1): 118-129.e4 (October 2018)Human monocyte-derived macrophages inhibit HCMV spread independent of classical antiviral cytokinesJ. Becker, V. Kinast, M. Doring, C. Lipps, V. Duran, J. Spanier, P. Tegtmeyer, D. Wirth, L. Cicin-Sain, A. Alcami and 1 other author(s). Virulence, 9 (1): 1669-1684 (2018)Microbiota-Induced Type I Interferons Instruct a Poised Basal State of Dendritic CellsL. Schaupp, S. Muth, L. Rogell, M. Kofoed-Branzk, F. Melchior, S. Lienenklaus, S. Ganal-Vonarburg, M. Klein, F. Guendel, T. Hain and 24 other author(s). Cell, 181 (5): 1080-1096 e19 (May 2020)Mice defective in interferon signaling help distinguish between primary and secondary pathological pathways in a mouse model of neuronal forms of Gaucher diseaseA. Vardi, S. Ben-Dor, S. Cho, U. Kalinke, J. Spanier, and A. Futerman. J Neuroinflammation, 17 (1): 265 (2020)Poly(I:C)-Encapsulating Nanoparticles Enhance Innate Immune Responses to the Tuberculosis Vaccine Bacille Calmette–Guérin (BCG) via Synergistic Activation of Innate Immune ReceptorsM. Speth, U. Repnik, E. Müller, J. Spanier, U. Kalinke, A. Corthay, and G. Griffiths. Mol Pharm, 14 (11): 4098-4112 (2017)PMID: 28974092.Concomitant TLR/RLH Signaling of Radioresistant and Radiosensitive Cells Is Essential for Protection against Vesicular Stomatitis Virus InfectionJ. Spanier, S. Lienenklaus, J. Paijo, A. Kessler, K. Borst, S. Heindorf, D. Baker, A. Kroger, S. Weiss, C. Detje and 2 other author(s). J Immunol, 193 (6): 3045-3054 (2014)Upon intranasal VSV infection astrocytes in the olfactory bulb are important IFN-beta producers that protect from lethal encephalitisC. Detje, S. Lienenklaus, C. Chhatbar, J. Spanier, C. Prajeeth, C. Soldner, M. Tovey, D. Schluter, S. Weiss, M. Stangel and 1 other author(s). J Virol, 89 (5): 2731-2738 (2015)Abortively infected astrocytes appear to represent the main source of interferon-β in the virus-infected brainC. Pfefferkorn, C. Kallfass, S. Lienenklaus, J. Spanier, U. Kalinke, M. Rieder, K. Conzelmann, T. Michiels, and P. Staeheli. J Virol, 90 (4): 2031-2038 (2015)A New RNA-Based Adjuvant Enhances Virus-Specific Vaccine Responses by Locally Triggering TLR- and RLH-Dependent EffectsA. Ziegler, C. Soldner, S. Lienenklaus, J. Spanier, S. Trittel, P. Riese, T. Kramps, S. Weiss, R. Heidenreich, E. Jasny and 4 other author(s). J Immunol, 198 (4): 1595-1605 (2017)

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Disambiguation of "Spanier, J"