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Peptide inhibitors of C3 activation as a novel strategy of complement inhibition for the treatment of paroxysmal nocturnal hemoglobinuria.

, , , , , , , , , , , , , , , , and . 123 (13): 2094--2101 (March 2014)
DOI: 10.1182/blood-2013-11-536573

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Regulators of complement activity mediate inhibitory mechanisms through a common C3b-binding mode., , , , , , , , , and 5 other author(s). The EMBO journal, 35 (10): 1133--1149 (May 2016)Peptide inhibitors of C3 activation as a novel strategy of complement inhibition for the treatment of paroxysmal nocturnal hemoglobinuria., , , , , , , , , and 7 other author(s). 123 (13): 2094--2101 (March 2014)A structurally dynamic N-terminal helix is a key functional determinant in staphylococcal complement inhibitor (SCIN) proteins., , , , , , , , and . Journal of Biological Chemistry, 288 (4): 2870--2881 (January 2013)Rational engineering of a minimized immune inhibitor with unique triple-targeting properties., , , , , , and . Journal of Immunology, 190 (11): 5712--5721 (June 2013)Diversity in the C3b Convertase Contact Residues and Tertiary Structures of the Staphylococcal Complement Inhibitor (SCIN) Protein Family, , , , , , , , and . Journal of Biological Chemistry, 287 (1): 628--640 (2012)Complement C3dg-mediated erythrophagocytosis: implications for paroxysmal nocturnal hemoglobinuria., , , , , , and . 126 (7): 891--894 (August 2015)