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New analogs of the clinical complement inhibitor compstatin with subnanomolar affinity and enhanced pharmacokinetic properties

H. Qu, D. Ricklin, H. Bai, H. Chen, E. Reis, M. Maciejewski, A. Tzekou, R. DeAngelis, R. Resuello, F. Lupu, P. Barlow, and J. Lambris. Immunobiology, 218 (4): 496--505 (April 2013)
DOI: 10.1016/j.imbio.2012.06.003

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Complement Fragment C3a Controls Mutual Cell Attraction during Collective Cell MigrationC. Carmona-Fontaine, E. Theveneau, A. Tzekou, M. Tada, M. Woods, K. Page, M. Parsons, J. Lambris, and R. Mayor. Developmental Cell, 21 (6): 1026--1037 (2011)Molecular Basis for Complement Recognition and Inhibition Determined by Crystallographic Studies of the Staphylococcal Complement Inhibitor (SCIN) Bound to C3c and C3bB. Garcia, K. Ramyar, A. Tzekou, D. Ricklin, W. McWhorter, J. Lambris, and B. Geisbrecht. Journal of Molecular Biology, 402 (1): 17--29 (2010)Allosteric inhibition of complement function by a staphylococcal immune evasion proteinH. Chen, D. Ricklin, M. Hammel, B. Garcia, W. McWhorter, G. Sfyroera, Y. Wu, A. Tzekou, S. Li, B. Geisbrecht and 2 other author(s). Proceedings of the National Academy of Sciences of the United States of America, 107 (41): 17621--17626 (2010)Protection of nonself surfaces from complement attack by factor H-binding peptides: implications for therapeutic medicine.Y. Wu, H. Qu, G. Sfyroera, A. Tzekou, B. Kay, B. Nilsson, K. Nilsson Ekdahl, D. Ricklin, and J. Lambris. Journal of Immunology, 186 (7): 4269--4277 (April 2011)New analogs of the clinical complement inhibitor compstatin with subnanomolar affinity and enhanced pharmacokinetic propertiesH. Qu, D. Ricklin, H. Bai, H. Chen, E. Reis, M. Maciejewski, A. Tzekou, R. DeAngelis, R. Resuello, F. Lupu and 2 other author(s). Immunobiology, 218 (4): 496--505 (April 2013)Complement anaphylatoxin C3a is a potent inducer of embryonic chick retina regeneration.T. Haynes, A. Luz-Madrigal, E. Reis, N. Echeverri Ruiz, E. Grajales-Esquivel, A. Tzekou, P. Tsonis, J. Lambris, and K. Del Rio-Tsonis. (2013)Crystallization of human complement component C3b in the presence of a staphylococcal complement-inhibitor protein (SCIN).B. Garcia, A. Tzekou, K. Ramyar, W. McWhorter, D. Ricklin, J. Lambris, and B. Geisbrecht. Acta crystallographica. Section F, Structural biology and crystallization communications, 65 (Pt 5): 482--485 (May 2009)Structures of C3b in Complex with Factors B and D Give Insight into Complement Convertase FormationF. Forneris, D. Ricklin, J. Wu, A. Tzekou, R. Wallace, J. Lambris, and P. Gros. Science, 330 (6012): 1816--1820 (2010)A molecular insight into complement evasion by the staphylococcal complement inhibitor protein family.D. Ricklin, A. Tzekou, B. Garcia, M. Hammel, W. McWhorter, G. Sfyroera, Y. Wu, V. Holers, A. Herbert, P. Barlow and 2 other author(s). Journal of Immunology, 183 (4): 2565--2574 (August 2009)Synthesis and Activity of Thioether-Containing Analogues of the Complement Inhibitor CompstatinP. Knerr, A. Tzekou, D. Ricklin, H. Qu, H. Chen, W. van der Donk, and J. Lambris. Acs Chemical Biology, 6 (7): 753--760 (2011)

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New analogs of the clinical complement inhibitor compstatin with subnanomolar affinity and enhanced pharmacokinetic properties

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copydeleteadd this publication to your clipboardcommunity posthistory of this postURLDOIBibTeXEndNoteAPAChicagoDIN 1505HarvardMSOffice XML New analogs of the clinical complement inhibitor compstatin with subnanomolar affinity and enhanced pharmacokinetic properties

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New analogs of the clinical complement inhibitor compstatin with subnanomolar affinity and enhanced pharmacokinetic properties