Despite the growing prevalence of depression in the Chinese elderly, there is conflicting evidence of life course socioeconomic position (SEP) and depression onset in China, and whether this association is akin to that observed in Western societies. We compared incident risk of mid–late life depression by childhood and adulthood SEP in China and England, a country where mental health inequality is firmly established. To read the full article, log in using your NHS OpenAthens details.
Little is known about the relationship between antidepressant treatment outcomes and underlying neurobiological mechanisms in patients with major depressive disorder (MDD). In this prospective study, we aimed to investigate how cortical thickness and subcortical volumes differed between remitter and non‐remitter patients with MDD.. To read the full article, log in using your NHS Athens details. To access full-text: click “Log in/Register” (top right hand side). Click ‘Institutional Login’ then select 'OpenAthens Federation', then ‘NHS England’. Enter your Athens details to view the article.
Correspondence. Recently, intranasal esketamine spray (Spravato®) was approved by the Food and Drug Administration in the United States of America for its use in treatment‐resistant depression (TRD), after clinical trials demonstrating its antidepressant efficacy and positive effects on suicidal ideation1. The antidepressant mechanisms of action of ketamine‐related molecules, ethical implications, and long‐term safety issues should be addressed.. To read the full article, log in using your NHS Athens details. To access full-text: click “Log in/Register” (top right hand side). Click ‘Institutional Login’ then select 'OpenAthens Federation', then ‘NHS England’. Enter your Athens details to view the article.
Several studies have found an increase in hippocampal volume following electroconvulsive therapy (ECT), but the effect on cortical thickness has been less investigated. We aimed to examine the effects of ECT on cortical thickness and their associations with clinical outcome.. To read the full article, log in using your NHS Athens details. To access full-text: click “Log in/Register” (top right hand side). Click ‘Institutional Login’ then select 'OpenAthens Federation', then ‘NHS England’. Enter your Athens details to view the article.
UCL Masters Students on network meta-analysis of drug treatment for generalised anxiety disorder, inc. Venlafaxine, Pregabalin, Escitalopram and Duloxetine.
To explore whether pain intensity has an indirect effect on quality of life through mediation of depression in patients with neuropathic pain.. To read the full article, log in using your NHS Athens details. To access full-text: click “Log in/Register” (top right hand side). Click ‘Institutional Login’ then select 'OpenAthens Federation', then ‘NHS England’. Enter your Athens details to view the article.
Cognitive‐behavioral therapy (CBT) is a highly effective treatment of health anxiety, but it remains unclear through which mechanisms treatment effects prevail. Some evidence suggests that patients acquire skills – understood as techniques helping them reach therapy goals – through psychotherapy. In the current study, an observer‐based rating scale for the Skills Assessment of Patients with Health Anxiety (SAPH) was developed and validated in a pilot study.. To read the full article, log in using your NHS Athens details. To access full-text: click “Log in/Register” (top right hand side). Click ‘Institutional Login’ then select 'OpenAthens Federation', then ‘NHS England’. Enter your Athens details to view the article.
Open access journal. Basic symptoms, defined as subjectively perceived disturbances in thought, perception and other essential mental processes, have been established as a predictor of psychotic disorders. However, the relationship between basic symptoms and family history of a transdiagnostic range of severe mental illness, including major depressive disorder, bipolar disorder and schizophrenia, has not been examined.
This guideline covers identifying and managing depression in children and young people aged 5 to 18 years. Based on the stepped-care model, it aims to improve recognition and assessment and promote effective treatments for mild and moderate to severe depression.
Depression is a common debilitating disease that affects individuals in all age groups. The impact of the diagnosis extends beyond the individual, with negative effects on mental health, physical health and social well-being. Self-efficacy has been referenced as an important aspect to the prognosis of mood disorders by conferring co-responsibility to the affected individual to face his/her health problems. Open Access Article
Examine the overall incidence of medically treated depression in Denmark among individuals 15–44 years old, and estimate the 5‐year cumulative incidence of psychiatric hospital care among individuals treated first in non‐hospital‐based care.. To read the full article, log in using your NHS Athens details. To access full-text: click “Log in/Register” (top right hand side). Click ‘Institutional Login’ then select 'OpenAthens Federation', then ‘NHS England’. Enter your Athens details to view the article.
To explore the temporal dynamic of antidepressant and antipsychotic co‐prescribing in real‐life conditions.. To read the full article, log in using your NHS Athens details. To access full-text: click “Log in/Register” (top right hand side). Click ‘Institutional Login’ then select 'OpenAthens Federation', then ‘NHS England’. Enter your Athens details to view the article.
Jonathon Tomlinson on a new systematic review and dose-response meta-analysis that looks at the optimal doses antidepressants for adults with depression.
Implications for practice and research:
>Largest meta-analysis for Generalised Anxiety Disorder (GAD) to date synthesising 89 trials.
>Adds ability to make research-based clinical decisions about medications for GAD that were not only funded from pharmaceutical companies.
>Future research, to determine the benefits of these identified medications concurrently with GAD and depression, may be a clinically helpful next step. To read the full article, log in using your NHS OpenAthens details.
Implications for practice and research:
>Practitioners need to consider the physical health of all people with depression in order to decrease their excess mortality.
>A community-based study is required to properly understand ethnic differences in the mortality rates of people with depression. To read the full article, log in using your NHS OpenAthens details.
Commentary. People with severe mental illness have higher mortality rates, culminating in about 20 years of lost life compared with that of the general population, and momentum is growing to reduce this inequality.1, 2 In the general population, neighbourhood social context is related to mortality, but whether such patterns also exist for people with severe mental illness has received little attention. Understanding this relationship could allow us to tailor social interventions for this distinctive population. The study by Jayati Das-Munshi and colleagues3 in The Lancet Psychiatry represents a welcome step in that direction, linking higher neighbourhood ethnic density to lower mortality rates among people with severe mental illness from ethnic minority backgrounds. These results raise the intriguing possibility that factors associated with ethnic density might promote longevity among people with severe mental illness.. Please contact the library to request a copy of this article - http://bit.ly/2HjNDf3
Neighbourhood social context might play a role in modifying mortality outcomes in severe mental illness, but has received little attention to date. Therefore, we aimed to assess in an ethnically diverse and urban location the association of neighbourhood-level characteristics and individual-level factors for all-cause, natural-cause, and unnatural-cause mortality in those with severe mental illness.. Please contact the library to request a copy of this article - http://bit.ly/2HjNDf3
Depression is the single largest contributor to non-fatal health loss worldwide. Second-generation antidepressants are the first-line option for pharmacological management of depression. Optimising their use is crucial in reducing the burden of depression; however, debate about their dose dependency and their optimal target dose is ongoing. We have aimed to summarise the currently available best evidence to inform this clinical question.. Please contact the library to request a copy of this article - http://bit.ly/2HjNDf3
N. Wallerstein, and N. Wiggins. La Santé en action(décembre 2018)Tiré du dossier EMPOWERMENT DES JEUNESURL : http://inpes.santepubliquefrance.fr/SLH/sommaires/446.asp?.
B. Lamboy, N. Cotton, and E. Hamel. La Santé en action(décembre 2018)Dossier "Prévention du vieillissement : interventions probantes" coordonné par Béatrice Lamboy, Nadine Cotton, Emmanuelle Hamel, Dagmar Soleymani.