Statins may act on an enzyme called endothelial nitric oxide synthase, which stimulates nitric oxide production. Increased nitric oxide has anti-inflammatory and anti-clotting effects...
HEMOSTASIS, THROMBOSIS, AND VASCULAR BIOLOGY. Judith Branger, Bernt van den Blink, Sebastiaan Weijer, Abhya Gupta, Sander J.H. van Deventer, C. Erik Hack, Maikel P. Peppelenbosch, and Tom van der Poll
Statins have nonlipid mechanisms that modify endothelial function, inflammatory responses, plaque stability, and thrombus formation. Benefits extend to patients with normal lipid levels due to statins' pleiotropic effects.
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Support, Non-U.S. Gov't England The Journal of physiology J Physiol.
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