The aim of this review is to identify and summarise the key in vitro evidence available to support the use of HydroTac (HRWD-2) to address specific aspects associated with the treatment of both acute and hard-to-heal wounds. To read the full article, choose “Institutional Login” and search for “Midlands Partnership”.
To synthesise the best available evidence regarding the effectiveness of using topical haemoglobin spray to promote healing in hard-to-heal wounds in adults. To read the full article, choose “Institutional Login” and search for “Midlands Partnership”.
The objective of this review was to present a comprehensive discussion of wound dressing adherence, including the mechanism of dressing adherence, adverse consequences, factors affecting adherence, tests to assess dressing adherence, and reduction of wound adherence. To read the full article, choose “Institutional Login” and search for “Midlands Partnership”.
This literature review confirms that acute and chronic wound infections are significantly differentiated by their cause (microbial phenotype), the subsequent host immune response and by the resulting clinical manifestations. Consequently, recognition of the type of wound infection followed by appropriate and timely therapy is required to improve wound healing outcomes while encouraging more judicious and responsible use of antibiotics. To read the full article, choose “Institutional Login” and search for “Midlands Partnership”.
High bacterial burden is one of several reasons that wounds fail to heal. This clinical trial evaluated the use of bacterial protease activity (BPA) as a biomarker to detect whether a wound was in the period of pathogenicity, prior to overt clinical signs. To read the full article, log in using your NHS OpenAthens details.
Martorell hypertensive ischaemic ulcers are often misdiagnosed and can be a clinical and therapeutic challenge. Controversy exists regarding both their underlying triggers and the type of treatment that should be carried out. This study was designed to compare the effectiveness of punch grafting and conventional therapy in pain reduction. To read the full article, log in using your NHS OpenAthens details.
To evaluate the influence of a wound healing protocol for stage III and IV pressure ulcers (PUs), and to determine the predictive power of specific sociodemographic and clinical characteristics on wound healing and infection. To read the full article, log in using your NHS OpenAthens details.
This study aimed to compare the effect of a novel sterile polyacrylate wound pad with activated carbon cloth treatment with a standard non-adhesive hydrocellular foam dressing with silver in reducing wound area. To read the full article, log in using your NHS OpenAthens details.
Objective: To compare the effectiveness of antiseptic solutions to that of non-antiseptic solutions in reducing wound infection rate, reducing bacterial load and improving wound healing. To read the full article, log in using your NHS OpenAthens details.
The aim of this case series was to retrospectively assess the impact on volume control and patients' quality of life (QOL) when a night-time garment was added to their previous compression regimen for a full 24-hour interval compression plan. To read the full article, log in using your NHS OpenAthens details.
This study was an open-labelled, non-comparative study assessing the clinical effectiveness of a coordinated wound dressing treatment regimen. To read the full article, log in using your NHS OpenAthens details.
Antimicrobial resistance (AMR) occurs (as a result of misuse, such as over-prescribing) when certain pathogens fail to respond to treatment with antimicrobials. Consequently, patients can become severely ill and possibly die. A strategy referred to as antimicrobial stewardship (AMS) has been introduced which reduces the impact of this antimicrobial misuse. To read the full article, log in using your NHS OpenAthens details.
Mechanical negative pressure wound therapy is an ultraportable, light weight and disposable single-use device that has been shown to promote wound healing. This study evaluated home use of a mechanically powered negative pressure wound therapy (NPWT) in diabetic foot wounds. To read the full article, log in using your NHS OpenAthens details.
The response of different critical acute and hard-to-heal wounds to an innovative wound care modality—direct application of cold atmospheric plasma (CAP)—was investigated in this clinical case series. To read the full article, log in using your NHS OpenAthens details.
A 48-year-old man suffered a cardiac event and was successfully resuscitated at home. He remained in vegetative state. During a lengthy hospital stay, he was weaned from mechanical ventilation and treated for urinary and pulmonary infections. On admission for aftercare, there were pressure ulcers in the presacral area and next to the scapula. A stage 3, right calf ulcer had a peripheral rim of new epithelium. A left ….... To read the full article, log in using your NHS OpenAthens details.
A nurse-led national wound care strategy aims to banish assumptions about ‘chronic’ wounds. To read the full article, log in using your MPFT NHS OpenAthens details.
Implementation of evidence-based care is central to achieving good results. In the UK, this involves implementing guidance from the National Institute for Health and Care Excellence (NICE). Here, Tracy Cowan, JWC consultant editor, reports on a conference that outlined recently published NICE guidance on UrgoStart for treating leg ulcers and diabetic foot ulcers, and described how to incorporate this into everyday practice to drive significant cost savings and improve patient outcomes. To read the full article, log in using your MPFT NHS OpenAthens details.
R. Frotscher, and M. Staat. 4th International Conference on Computational and Mathematical Biomedical Engineering - CMBE2015, 29 June - 1 July 2015, Cachan (Paris), France, CMBE Zeta Computational Resources Ltd., Swansea, UK, (2015)