Letter. We read with interest the stimulating article by McDonald et al. who have elegantly reviewed the scientific advances of Parkinson’s Disease (PD) since James Parkinson’s original description [1]. In the last decades, significant advances have been achieved regarding pathophysiology and symptomatic treatments, but critically important issues are still under discussion, such as the need to modify disease progression [1, 2]. Another important aspect, not frequently discussed in the literature, that should also be addressed, is the mortality in PD..... To read the full article, log in using your MPFT NHS OpenAthens details. SSOTP (legacy account) - You can request a copy of this article by replying to this email. Please ensure you are clear which article you are requesting.