Even the lowest dose of modafinil, an ampakine, improved the wakefulness and cognitive performance of sleep-deprived people; they work in part by boosting glutamate, a key neurotransmitter that facilitates learning & learn and encodes memory.
We must optimize stent deployment & maintain a registry of how well (or poorly) we use drug-eluting stents. Instead of asking “Which stent?” or “How much anti-platelet therapy?” we must ask “How effectively are we deploying our stents?”
AMPA modulators might ameliorate memory deficits that occur in dementia, such as Alzheimer's disease (AD). However, AMPA receptor mediated excitotoxicity may occur with excessive AMPA receptor activation which occurs in seizures or ischaemia and positive