Evaluation of Cypher Sirolimus Eluting Stent in Patients Undergoing Elective Revascularization of Nonacute Total Coronary Occlusions (TCO). Cordis Corp. Columbia Presbyterian, NYC. 2006-2011. (Not currently recruiting)
Major limitation of percutaneous therapy (PCI) for the treatment of chronic total occlusions (CTOs) is the inability to cross with a wire. Recanalization with Intraluminal Wire, combines guidance of wire tip and radiofrequency ablation.
Every 3rd coronary angiography patient presents 1+ total arterial occlusion. Guidewire failure often precludes subsequent repair of the lesion in the cardiac cath lab; many of these patients are ultimately managed surgically or medically.
Techniques for penetrating chronic total occlusion (CTO) to ensure complete revascularization using percutaneous coronary techniques. Success is only 50–75%, even in the best hands. How to improve?