Symptoms of psychosis in patients with Alzheimer disease may be the expression of a pathological subtype associated with an accelerated cognitive and functional deterioration portending a hastened mortality.1 The proposed National Institute of Mental Health Research Domain Criteria initiative provides a framework for conceptualizing the common neurobiological underpinnings of symptom domains such as psychosis that transcend individual diagnostic categories to facilitate translational research.2 Gur et al3 suggest that highly implementable tasks measuring facial affective processing can be used to assay social cognitive integrity in psychotic disorders within the National Institute of Mental Health Research Domain Criteria framework. Although McLellan et al4 report that facial affective processing is degraded in Alzheimer disease, to our knowledge no published studies have investigated the association between this impairment and the psychotic phenotype. We report on facial affective processing performance in a longitudinal cohort of healthy elderly control individuals and participants with mild cognitive impairment (MCI) or Alzheimer disease at baseline, with and without symptoms of psychosis over the course of the study.https://blackwells.co.uk/bookshop/product/Evidence-Based-Assessment-in-ASD-Autism-Spectrum-Disorder-by-Kenneth-Aitken-author/9781849055291
This meta-analysis compares early intervention services with treatment as usual for patients with early-phase psychosis.. Please contact the library to request a copy of this article - http://bit.ly/1Xyazai
The management of schizophrenia is evolving towards a more comprehensive model based on functional recovery. The concept of functional recovery goes beyond clinical remission and encompasses multiple aspects of the patient’s life, making it difficult to settle on a definition and to develop reliable assessment criteria. In this consensus process based on a panel of experts in schizophrenia, we aimed to provide useful insights on functional recovery and its involvement in clinical practice and clinical research.
Open access. Very late (aged ≥60 years) onset schizophrenia-like psychosis occurs frequently but no placebo-controlled, randomised trials have assessed the efficacy and risks of antipsychotic treatment. We investigated whether low-dose amisulpride (100 mg daily) is superior to placebo in reducing psychosis symptoms over 12 weeks and whether any benefit is maintained by continuing treatment after 12 weeks.
Open access. Comment. Robert Howard and colleagues should be commended for doing the first randomised controlled trial of an antipsychotic agent in patients diagnosed with very late-onset schizophrenia-like psychosis. Individuals with this diagnosis are notoriously difficult to engage in treatment.....
People with severe mental illnesses (SMI) such as schizophrenia and bipolar disorder have an increased risk of developing type 2 diabetes and have poorer health outcomes than those with diabetes alone. To maintain good diabetes control, people with diabetes are advised to engage in several self-management behaviours. The aim of this study was to identify barriers or enablers of diabetes self-management experienced by people with SMI.
Routinely monitoring of symptoms and medical needs can improve the diagnostics and treatment of medical problems, including psychiatric. However, several studies show that few clinicians use Routine Outcome Monitoring (ROM) in their daily work. We describe the development and first evaluation of a ROM based computerized clinical decision aid, Treatment-E-Assist (TREAT) for the treatment of psychotic disorders.
Letter. Login at top right hand side of page using your MPFT NHS OpenAthens for full text. SSOTP (legacy account)- Please contact the library to receive a copy of this article - http://bit.ly/1Xyazai
Case report.. Login at top right hand side of page using your MPFT NHS OpenAthens for full text. SSOTP (legacy account)- Please contact the library to receive a copy of this article - http://bit.ly/1Xyazai
Psychiatric Rehabilitation Journal Vol. 41, Iss. 2, (Jun 2018): 109-117.
Objective: There is a paucity of accessible, evidence-based tools for caregivers of individuals with schizophrenia. This study examines changes in the self-assessed and caregiver-assessed outcomes of people with schizophrenia after exposure to a cognitive adaptation training (CAT) guide that addressed pragmatic, in-home approaches to offset the cognitive impacts of the illness.. To read the full article, log in using your NHS OpenAthens details.
Paranoid schizophrenia is characterised by an increased risk of suicide and homicide. Little is known about the influence of personality dimensions as determinants for suicidal and homicidal behaviour within this condition. We assessed the differences among suicidal, homicidal and non-aggressive adult male in-patients with ICD-10 paranoid schizophrenia.. Please contact the library to request a copy of this article - http://bit.ly/1Xyazai
In this historical control study of 1234 patients with first-episode schizophrenia-spectrum disorders (617 each in the early intervention and standard care groups), patients receiving a 2-year early intervention service had a significantly lower suicide rate during 12 years, with the main difference observed during the first 3 years.. Please contact the library to request a copy of this article - http://bit.ly/1Xyazai
Editorial-In this issue of JAMA Psychiatry, Chan et al1 present new and important findings on the long-term effects of early intervention programs for patients with first-episode psychosis on the risk of suicide. Using a historical cohort matched to 617 individuals included in the early intervention group, the authors show that the 2-year intervention significantly reduced the suicide rate in the first 3 years after initiation of treatment and that there was no relapse in suicide rates after the initial 3 years. Throughout the 12-year follow-up period, 27 (4.4%) died by suicide in the intervention group and 46 (7.5%), in the control group. Given the relative rarity of suicide, it requires a large sample to be able to show association of any intervention when death by suicide is the primary outcome. To our knowledge, this study1 is the first to show an association between suicide rates and psychosocial interventions in patients with first-episode psychosis.. Please contact the library to request a copy of this article - http://bit.ly/1Xyazai
Cognitive behaviour therapy is recommended internationally as a treatment for psychosis (targeting symptoms such as auditory hallucinations, or “voices”). Yet mental health services are commonly unable to offer such resource‐intensive psychological interventions. Brief, symptom‐specific and less resource‐intensive therapies are being developed as one initiative to increase access. However, as access increases, so might the risk of offering therapy to clients who are not optimally disposed to engage with and benefit from therapy. Thus, it is important to identify who is most/least likely to engage with and benefit from therapy, and when.. To read the full article, log in using your SSSFT NHS OpenAthens details. SSOTP - You can request a copy of this article by replying to this email. Please ensure you are clear which article you are requesting.
The authors conducted a systematic review and meta-analysis to determine whether the risk of psychosis is higher in past or future episodes in patients with major depression with psychotic features than in patients with nonpsychotic depression.. Login at top right hand side of page using your SSSFT NHS OpenAthens for full text. SSOTP- Please contact the library to receive a copy of this article - http://bit.ly/1Xyazai
Research demonstrates negative perceptions of individuals with intellectual disabilities (ID) and individuals with schizophrenia, but no study has examined ID with a co‐morbid psychiatric disorder. The present study examined the social distance desired from and perceptions of dangerousness of ID, schizophrenia and co‐morbid schizophrenia and ID and examined the impact of providing a label for the behaviours presented in a vignette.. To read the full article, log in using your SSSFT NHS OpenAthens details. SSOTP - You can request a copy of this article by replying to this email. Please ensure you are clear which article you are requesting.
Criminal victimization has been associated with elevated risk for psychotic symptoms in the United Kingdom, but has not been studied in low‐ and middle‐income countries (LMICs). Understanding whether crime exposure may play a role in the social etiology of psychosis could help guide prevention and intervention efforts.. To read the full article, log in using your SSSFT NHS OpenAthens details. SSOTP - You can request a copy of this article by replying to this email. Please ensure you are clear which article you are requesting.
This study prospectively evaluated outcomes of OnTrackNY, a statewide coordinated specialty care (CSC) program for treatment of early psychosis in community settings, as well as predictors of outcomes.. Login at top right hand side of page using your SSSFT NHS OpenAthens for full text. SSOTP- Please contact the library to receive a copy of this article - http://bit.ly/1Xyazai
Multiple system atrophy (MSA) is an adult-onset, rare, and progressive neurodegenerative disorder characterized by a varying combination of autonomic failure, cerebellar ataxia, and parkinsonism. MSA is categorized as MSA-P with predominant parkinsonism, and as MSA-C with predominant cerebellar features. The prevalence of MSA has been reported to be between 1.86 and 4.9 cases per 100,000 individuals. In contrast, approximately 1% of the population is affected by schizophrenia during their lifetime; therefore, MSA-P comorbidity is very rare in schizophrenic patients. However, when the exacerbation or progression of parkinsonism occurs in patients with schizophrenia treated with antipsychotics, it is necessary to consider rare neurodegenerative disorders, including MSA-P, in the differential diagnosis of parkinsonism.