Loneliness is prevalent among individuals with mental illnesses. This cross-sectional survey study examined the moderating effects of self-esteem and perceived support from families and friends on the association of loneliness with suicide risk and depression in individuals with schizophrenia. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
Suicide risk is elevated among individuals at clinical high risk for psychosis (CHR-P). The current study examined variability in suicidal ideation during treatment for individuals at CHR-P.
Patients with schizophrenia have a significant risk of self-harm. We aimed to explore the dynamic relationship between symptomatology, functioning and deliberate self-harm (DSH) and evaluate the feasibility of developing a self-harm risk prediction tool for patients with first-episode schizophrenia (FES). To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
Open access. Suicide is a leading cause of premature death in people with a diagnosis of schizophrenia. Although exposure to stressors can play a part in the pathways to death by suicide, there is evidence that some people with a diagnosis of schizophrenia can be resilient to the impact of suicide triggers.
More than 90% of people who attempt suicide have a psychiatric diagnosis; however, twin and family studies suggest that the genetic etiology of suicide attempt is partially distinct from that of the psychiatric disorders themselves. The authors present the largest genome-wide association study (GWAS) on suicide attempt, using cohorts of individuals with major depressive disorder, bipolar disorder, and schizophrenia from the Psychiatric Genomics Consortium.. Login at top right hand side of page using your MPFT NHS OpenAthens for full text.
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Letter. Suicide is one of the leading causes of premature death among individuals with schizophrenia and psychotic spectrum disorders (1). Suicide and suicide attempts occur at a significantly greater rate in schizophrenia than in the general population. Common estimates are that 10% of people with schizophrenia will eventually have a completed suicide, and that attempts are made at two to five times that rate.. To read the full article, log in using your NHS Athens details. To access full-text: click “Log in/Register” (top right hand side). Click ‘Institutional Login’ then select 'OpenAthens Federation', then ‘NHS England’. Enter your Athens details to view the article.
Associations between suicidality and lipid dysregulation are documented in mental illness, but the potential role of leptin remains unclear. We examined the association between leptin and suicidal behaviour in schizophrenia, together with the influence of other clinical and biological indices.. To read the full article, log in using your NHS Athens details. To access full-text: click “Log in/Register” (top right hand side). Click ‘Institutional Login’ then select 'OpenAthens Federation', then ‘NHS England’. Enter your Athens details to view the article.
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Open access. Bipolar and other psychiatric disorders are associated with considerably increased risk of suicidal behaviour, which may include self-poisoning with medication used to treat the disorder. Therefore, choice of medication for treatment should include consideration of toxicity, especially for patients at risk. The aim of this study was to estimate the relative toxicity of specific drugs within two drug categories, antipsychotics and mood stabilizers, using large-scale databases to provide evidence that could assist clinicians in making decisions about prescribing, especially for patients at risk of suicidal behaviour.
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Free access. Between 5% and 10% of people with psychosis will die by suicide, a rate which is 20–75 times higher than the general population. This risk is even greater in those not taking antipsychotic medication. We examined whether negative appraisals of psychotic experiences and negative metacognitive beliefs about losing mental control mediated a relationship between psychotic symptoms and suicidal ideation in this group.
Individuals with psychotic disorders are at high risk of suicidal behavior. The study examined whether response to item 9 of the Patient Health Questionnaire (PHQ-9), which asks about thoughts of death or self-harm, predicts suicidal behavior among outpatients with diagnoses of psychotic disorders.. Login at top right hand side of page using your MPFT NHS OpenAthens for full text.
Psychological Medicine; Cambridge Vol. 48, Iss. 11, (Aug 2018): 1915-1916. DOI:10.1017/S0033291718000764
While the large sample size (N = 2245) and use of an early childhood sample (ages 6–12 years) are notable strengths of the study, the greatest advance comes from how the authors conceptualized the childhood trauma exposure construct. [...]research has suggested that much of the co-occurrence between psychotic experiences and suicidal behavior can be accounted for by shared risk factors, particularly those that are associated with elevated stress and exposure to trauma (DeVylder et al. 2015b) and arise in the context of greater multi-morbidity and clinical severity (Kelleher et al. 2014b).. To read the full article, log in using your NHS OpenAthens details.
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Paranoid schizophrenia is characterised by an increased risk of suicide and homicide. Little is known about the influence of personality dimensions as determinants for suicidal and homicidal behaviour within this condition. We assessed the differences among suicidal, homicidal and non-aggressive adult male in-patients with ICD-10 paranoid schizophrenia.. Please contact the library to request a copy of this article - http://bit.ly/1Xyazai
In this historical control study of 1234 patients with first-episode schizophrenia-spectrum disorders (617 each in the early intervention and standard care groups), patients receiving a 2-year early intervention service had a significantly lower suicide rate during 12 years, with the main difference observed during the first 3 years.. Please contact the library to request a copy of this article - http://bit.ly/1Xyazai
Editorial-In this issue of JAMA Psychiatry, Chan et al1 present new and important findings on the long-term effects of early intervention programs for patients with first-episode psychosis on the risk of suicide. Using a historical cohort matched to 617 individuals included in the early intervention group, the authors show that the 2-year intervention significantly reduced the suicide rate in the first 3 years after initiation of treatment and that there was no relapse in suicide rates after the initial 3 years. Throughout the 12-year follow-up period, 27 (4.4%) died by suicide in the intervention group and 46 (7.5%), in the control group. Given the relative rarity of suicide, it requires a large sample to be able to show association of any intervention when death by suicide is the primary outcome. To our knowledge, this study1 is the first to show an association between suicide rates and psychosocial interventions in patients with first-episode psychosis.. Please contact the library to request a copy of this article - http://bit.ly/1Xyazai