Alzheimer’s disease (AD) remains as a silent and increasing threat to public health. More than 200 clinical trials for AD have ended with disappointing results and basically empty-handed. The amyloid hypothesis as a primary culprit of AD still centralises most of the efforts in the academic and private sectors, but we need to start to explore alternative avenues for early diagnosis and development of effective therapeutic approaches to treat or slow down the progression of neurodegeneration.. To read the full article, log in using your NHS OpenAthens details.
Individual motor improvement after deep brain stimulation (DBS) of the subthalamic nucleus (STN) for Parkinson’s disease (PD) varies considerably. Stereotactic targeting of the dorsolateral sensorimotor part of the STN is considered paramount for maximising effectiveness, but studies employing the midcommissural point (MCP) as anatomical reference failed to show correlation between DBS location and motor improvement. The medial border of the STN as reference may provide better insight in the relationship between DBS location and clinical outcome.. To read the full article, log in using your NHS OpenAthens details.
Letter. . To read the full article, log in using your SSSFT NHS OpenAthens details. SSOTP - You can request a copy of this article by replying to this email. Please ensure you are clear which article you are requesting.
Letter. . To read the full article, log in using your SSSFT NHS OpenAthens details. SSOTP - You can request a copy of this article by replying to this email. Please ensure you are clear which article you are requesting.
Letter. . To read the full article, log in using your SSSFT NHS OpenAthens details. SSOTP - You can request a copy of this article by replying to this email. Please ensure you are clear which article you are requesting.
Open access. The aim of this review is to determine whether automated computerised tests accurately identify patients with progressive cognitive impairment and, if so, to investigate their role in monitoring disease progression and/or response to treatment.
To determine whether intrathecal baclofen (ITB) therapy improves performance and performance satisfaction in goal areas identified by patients' parents.. Please contact the library to request a copy of this article - http://bit.ly/1Xyazai
The purpose of this systematic review was to provide an up-to-date global overview of the separate prevalences of motor and cognitive delays and cerebral palsy (CP) in very preterm (VPT) and very-low-birthweight (VLBW) infants.. Please contact the library to request a copy of this article - http://bit.ly/1Xyazai
To describe health-related quality of life of Australian children and adolescents with Down syndrome and compare it with norm-referenced data.. Please contact the library to request a copy of this article - http://bit.ly/1Xyazai
Blog post. Further investigation of the effects of psilocybin may lead to new interventions to create positive changes in healthy people. By Emma Young
There is a great demand for non-medical treatment and support targeting the needs of adolescents and young adults with autism spectrum disorder (ASD) and attention-deficit/hyperactivity disorder (ADHD). There is also a lack of qualitative studies providing in-depth insight into these individuals’ own experiences within this area. The current study aimed to explore how adolescents and young adults with ADHD, ASD or both experienced taking part in an internet-based support and coaching intervention.
Optimising quality of life (QOL) for service users in a forensic hospital is an important treatment objective. The factors which contribute to QOL in this setting are currently unclear. The aim of this study was to analyse the predictors of QOL amongst service users within an inpatient forensic mental health hospital.