%0 Journal Article %1 Bojesen.2013 %A Bojesen, Stig E. %A Pooley, Karen A. %A Johnatty, Sharon E. %A Beesley, Jonathan %A Michailidou, Kyriaki %A Tyrer, Jonathan P. %A Edwards, Stacey L. %A Pickett, Hilda A. %A Shen, Howard C. %A Smart, Chanel E. %A Hillman, Kristine M. %A Mai, Phuong L. %A Lawrenson, Kate %A Stutz, Michael D. %A Lu, Yi %A Karevan, Rod %A Woods, Nicholas %A Johnston, Rebecca L. %A French, Juliet D. %A Chen, Xiaoqing %A Weischer, Maren %A Nielsen, Sune F. %A Maranian, Melanie J. %A Ghoussaini, Maya %A Ahmed, Shahana %A Baynes, Caroline %A Bolla, Manjeet K. %A Wang, Qin %A Dennis, Joe %A McGuffog, Lesley %A Barrowdale, Daniel %A Lee, Andrew %A Healey, Sue %A Lush, Michael %A Tessier, Daniel C. %A Vincent, Daniel %A Bacot, Françis %A Vergote, Ignace %A Lambrechts, Sandrina %A Despierre, Evelyn %A Risch, Harvey A. %A González-Neira, Anna %A Rossing, Mary Anne %A Pita, Guillermo %A Doherty, Jennifer A. %A Alvarez, Nuria %A Larson, Melissa C. %A Fridley, Brooke L. %A Schoof, Nils %A Chang-Claude, Jenny %A Cicek, Mine S. %A Peto, Julian %A Kalli, Kimberly R. %A Broeks, Annegien %A Armasu, Sebastian M. %A Schmidt, Marjanka K. %A Braaf, Linde M. %A Winterhoff, Boris %A Nevanlinna, Heli %A Konecny, Gottfried E. %A Lambrechts, Diether %A Rogmann, Lisa %A Guénel, Pascal %A Teoman, Attila %A Milne, Roger L. %A Garcia, Joaquin J. %A Cox, Angela %A Shridhar, Vijayalakshmi %A Burwinkel, Barbara %A Marme, Frederik %A Hein, Rebecca %A Sawyer, Elinor J. %A Haiman, Christopher A. %A Wang-Gohrke, Shan %A Andrulis, Irene L. %A Moysich, Kirsten B. %A Hopper, John L. %A Odunsi, Kunle %A Lindblom, Annika %A Giles, Graham G. %A Brenner, Hermann %A Simard, Jacques %A Lurie, Galina %A Fasching, Peter A. %A Carney, Michael E. %A Radice, Paolo %A Wilkens, Lynne R. %A Swerdlow, Anthony %A Goodman, Marc T. %A Brauch, Hiltrud %A Garcia-Closas, Montserrat %A Hillemanns, Peter %A Winqvist, Robert %A Dürst, Matthias %A Devilee, Peter %A Runnebaum, Ingo %A Jakubowska, Anna %A Lubinski, Jan %A Mannermaa, Arto %A Butzow, Ralf %A Bogdanova, Natalia V. %A Dörk, Thilo %A Pelttari, Liisa M. %A Zheng, Wei %A Leminen, Arto %A Anton-Culver, Hoda %A Bunker, Clareann H. %A Kristensen, Vessela %A Ness, Roberta B. %A Muir, Kenneth %A Edwards, Robert %A Meindl, Alfons %A Heitz, Florian %A Matsuo, Keitaro %A Du Bois, Andreas %A Wu, Anna H. %A Harter, Philipp %A Teo, Soo-Hwang %A Schwaab, Ira %A Shu, Xiao-Ou %A Blot, William %A Hosono, Satoyo %A Kang, Daehee %A Nakanishi, Toru %A Hartman, Mikael %A Yatabe, Yasushi %A Hamann, Ute %A Karlan, Beth Y. %A Sangrajrang, Suleeporn %A Kjaer, Susanne Krüger %A Gaborieau, Valerie %A Jensen, Allan %A Eccles, Diana %A Høgdall, Estrid %A Shen, Chen-Yang %A Brown, Judith %A Woo, Yin Ling %A Shah, Mitul %A Azmi, Mat Adenan Noor, %A Luben, Robert %A Omar, Siti Zawiah %A Czene, Kamila %A Vierkant, Robert A. %A Nordestgaard, Børge G. %A Flyger, Henrik %A Vachon, Celine %A Olson, Janet E. %A Wang, Xianshu %A Levine, Douglas A. %A Rudolph, Anja %A Weber, Rachel Palmieri %A Flesch-Janys, Dieter %A Iversen, Edwin %A Nickels, Stefan %A Schildkraut, Joellen M. %A Silva, Isabel Dos Santos, %A Cramer, Daniel W. %A Gibson, Lorna %A Terry, Kathryn L. %A Fletcher, Olivia %A Vitonis, Allison F. %A van der Schoot, C Ellen, %A Poole, Elizabeth M. %A Hogervorst, Frans B L, %A Tworoger, Shelley S. %A Liu, Jianjun %A Bandera, Elisa V. %A Li, Jingmei %A Olson, Sara H. %A Humphreys, Keith %A Orlow, Irene %A Blomqvist, Carl %A Rodriguez-Rodriguez, Lorna %A Aittomäki, Kristiina %A Salvesen, Helga B. %A Muranen, Taru A. %A Wik, Elisabeth %A Brouwers, Barbara %A Krakstad, Camilla %A Wauters, Els %A Halle, Mari K. %A Wildiers, Hans %A Kiemeney, Lambertus A. %A Mulot, Claire %A Aben, Katja K. %A Laurent-Puig, Pierre %A Altena, Anne Mvan %A Truong, Thérèse %A Massuger, Leon F A G, %A Benitez, Javier %A Pejovic, Tanja %A Perez, Jose Ignacio Arias, %A Hoatlin, Maureen %A Zamora, M. Pilar %A Cook, Linda S. %A Balasubramanian, Sabapathy P. %A Kelemen, Linda E. %A Schneeweiss, Andreas %A Le, Nhu D. %A Sohn, Christof %A Brooks-Wilson, Angela %A Tomlinson, Ian %A Kerin, Michael J. %A Miller, Nicola %A Cybulski, Cezary %A Henderson, Brian E. %A Menkiszak, Janusz %A Schumacher, Fredrick %A Wentzensen, Nicolas %A Le Marchand, Loic %A Yang, Hannah P. %A Mulligan, Anna Marie %A Glendon, Gord %A Engelholm, Svend Aage %A Knight, Julia A. %A Høgdall, Claus K. %A Apicella, Carmel %A Gore, Martin %A Tsimiklis, Helen %A Song, Honglin %A Southey, Melissa C. %A Jager, Agnes %A den Ouweland, Ans M Wvan, %A Brown, Robert %A Martens, John W M, %A Flanagan, James M. %A Kriege, Mieke %A Paul, James %A Margolin, Sara %A Siddiqui, Nadeem %A Severi, Gianluca %A Whittemore, Alice S. %A Baglietto, Laura %A McGuire, Valerie %A Stegmaier, Christa %A Sieh, Weiva %A Müller, Heiko %A Arndt, Volker %A Labrèche, France %A Gao, Yu-Tang %A Goldberg, Mark S. %A Yang, Gong %A Dumont, Martine %A McLaughlin, John R. %A Hartmann, Arndt %A Ekici, Arif B. %A Beckmann, Matthias W. %A Phelan, Catherine M. %A Lux, Michael P. %A Permuth-Wey, Jenny %A Peissel, Bernard %A Sellers, Thomas A. %A Ficarazzi, Filomena %A Barile, Monica %A Ziogas, Argyrios %A Ashworth, Alan %A Gentry-Maharaj, Aleksandra %A Jones, Michael %A Ramus, Susan J. %A Orr, Nick %A Menon, Usha %A Pearce, Celeste L. %A Brüning, Thomas %A Pike, Malcolm C. %A Ko, Yon-Dschun %A Lissowska, Jolanta %A Figueroa, Jonine %A Kupryjanczyk, Jolanta %A Chanock, Stephen J. %A Dansonka-Mieszkowska, Agnieszka %A Jukkola-Vuorinen, Arja %A Rzepecka, Iwona K. %A Pylkäs, Katri %A Bidzinski, Mariusz %A Kauppila, Saila %A Hollestelle, Antoinette %A Seynaeve, Caroline %A Tollenaar, Rob A E M, %A Durda, Katarzyna %A Jaworska, Katarzyna %A Hartikainen, Jaana M. %A Kosma, Veli-Matti %A Kataja, Vesa %A Antonenkova, Natalia N. %A Long, Jirong %A Shrubsole, Martha %A Deming-Halverson, Sandra %A Lophatananon, Artitaya %A Siriwanarangsan, Pornthep %A Stewart-Brown, Sarah %A Ditsch, Nina %A Lichtner, Peter %A Schmutzler, Rita K. %A Ito, Hidemi %A Iwata, Hiroji %A Tajima, Kazuo %A Tseng, Chiu-Chen %A Stram, Daniel O. %A van den Berg, David, %A Yip, Cheng Har %A Ikram, M. Kamran %A Teh, Yew-Ching %A Cai, Hui %A Lu, Wei %A Signorello, Lisa B. %A Cai, Qiuyin %A Noh, Dong-Young %A Yoo, Keun-Young %A Miao, Hui %A Iau, Philip Tsau-Choong %A Teo, Yik Ying %A McKay, James %A Shapiro, Charles %A Ademuyiwa, Foluso %A Fountzilas, George %A Hsiung, Chia-Ni %A Yu, Jyh-Cherng %A Hou, Ming-Feng %A Healey, Catherine S. %A Luccarini, Craig %A Peock, Susan %A Stoppa-Lyonnet, Dominique %A Peterlongo, Paolo %A Rebbeck, Timothy R. %A Piedmonte, Marion %A Singer, Christian F. %A Friedman, Eitan %A Thomassen, Mads %A Offit, Kenneth %A Hansen, Thomas V O, %A Neuhausen, Susan L. %A Szabo, Csilla I. %A Blanco, Ignacio %A Garber, Judy %A Narod, Steven A. %A Weitzel, Jeffrey N. %A Montagna, Marco %A Olah, Edith %A Godwin, Andrew K. %A Yannoukakos, Drakoulis %A Goldgar, David E. %A Caldes, Trinidad %A Imyanitov, Evgeny N. %A Tihomirova, Laima %A Arun, Banu K. %A Campbell, Ian %A Mensenkamp, Arjen R. %A van Asperen, Christi J, %A van Roozendaal, Kees E P, %A Meijers-Heijboer, Hanne %A Collée, J. Margriet %A Oosterwijk, Jan C. %A Hooning, Maartje J. %A Rookus, Matti A. %A van der Luijt, Rob B, %A Os, Theo A Mvan, %A Evans, D. Gareth %A Frost, Debra %A Fineberg, Elena %A Barwell, Julian %A Walker, Lisa %A Kennedy, M. John %A Platte, Radka %A Davidson, Rosemarie %A Ellis, Steve D. %A Cole, Trevor %A Bressac-de Paillerets, Brigitte %A Buecher, Bruno %A Damiola, Francesca %A Faivre, Laurence %A Frenay, Marc %A Sinilnikova, Olga M. %A Caron, Olivier %A Giraud, Sophie %A Mazoyer, Sylvie %A Bonadona, Valérie %A Caux-Moncoutier, Virginie %A Toloczko-Grabarek, Aleksandra %A Gronwald, Jacek %A Byrski, Tomasz %A Spurdle, Amanda B. %A Bonanni, Bernardo %A Zaffaroni, Daniela %A Giannini, Giuseppe %A Bernard, Loris %A Dolcetti, Riccardo %A Manoukian, Siranoush %A Arnold, Norbert %A Engel, Christoph %A Deissler, Helmut %A Rhiem, Kerstin %A Niederacher, Dieter %A Plendl, Hansjoerg %A Sutter, Christian %A Wappenschmidt, Barbara %A Borg, Ake %A Melin, Beatrice %A Rantala, Johanna %A Soller, Maria %A Nathanson, Katherine L. %A Domchek, Susan M. %A Rodriguez, Gustavo C. %A Salani, Ritu %A Kaulich, Daphne Gschwantler %A Tea, Muy-Kheng %A Paluch, Shani Shimon %A Laitman, Yael %A Skytte, Anne-Bine %A Kruse, Torben A. %A Jensen, Uffe Birk %A Robson, Mark %A Gerdes, Anne-Marie %A Ejlertsen, Bent %A Foretova, Lenka %A Savage, Sharon A. %A Lester, Jenny %A Soucy, Penny %A Kuchenbaecker, Karoline B. %A Olswold, Curtis %A Cunningham, Julie M. %A Slager, Susan %A Pankratz, Vernon S. %A Dicks, Ed %A Lakhani, Sunil R. %A Couch, Fergus J. %A Hall, Per %A Monteiro, Alvaro N A, %A Gayther, Simon A. %A Pharoah, Paul D P, %A Reddel, Roger R. %A Goode, Ellen L. %A Greene, Mark H. %A Easton, Douglas F. %A Berchuck, Andrew %A Antoniou, Antonis C. %A Chenevix-Trench, Georgia %A Dunning, Alison M. %D 2013 %J Nature genetics %K Alternative_Splicing Breast_Neoplasms/etiology/pathology Case-Control_Studies Chromatin/genetics DNA_Methylation Female Gene_Expression_Profiling Genetic_Loci/genetics Genetic_Predisposition_to_Disease Genome-Wide_Association_Study Genotype Humans Luciferases/metabolism Oligonucleotide_Array_Sequence_Analysis Ovarian_Neoplasms/etiology/pathology Polymorphism,_Single_Nucleotide/genetics RNA,_Messenger/genetics Real-Time_Polymerase_Chain_Reaction Reverse_Transcriptase_Polymerase_Chain_Reaction Risk_Factors Telomerase/genetics Telomere/genetics Tumor_Markers,_Biological/genetics %N 4 %P 371-84, 384e1-2 %T Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer %V 45 %X TERT-locus SNPs and leukocyte telomere measures are reportedly associated with risks of multiple cancers. Using the Illumina custom genotyping array iCOGs, we analyzed ∼480 SNPs at the TERT locus in breast (n = 103,991), ovarian (n = 39,774) and BRCA1 mutation carrier (n = 11,705) cancer cases and controls. Leukocyte telomere measurements were also available for 53,724 participants. Most associations cluster into three independent peaks. The minor allele at the peak 1 SNP rs2736108 associates with longer telomeres (P = 5.8 × 10(-7)), lower risks for estrogen receptor (ER)-negative (P = 1.0 × 10(-8)) and BRCA1 mutation carrier (P = 1.1 × 10(-5)) breast cancers and altered promoter assay signal. The minor allele at the peak 2 SNP rs7705526 associates with longer telomeres (P = 2.3 × 10(-14)), higher risk of low-malignant-potential ovarian cancer (P = 1.3 × 10(-15)) and greater promoter activity. The minor alleles at the peak 3 SNPs rs10069690 and rs2242652 increase ER-negative (P = 1.2 × 10(-12)) and BRCA1 mutation carrier (P = 1.6 × 10(-14)) breast and invasive ovarian (P = 1.3 × 10(-11)) cancer risks but not via altered telomere length. The cancer risk alleles of rs2242652 and rs10069690, respectively, increase silencing and generate a truncated TERT splice variant.

@article{Bojesen.2013, abstract = {TERT-locus SNPs and leukocyte telomere measures are reportedly associated with risks of multiple cancers. Using the Illumina custom genotyping array iCOGs, we analyzed ∼480 SNPs at the TERT locus in breast (n = 103,991), ovarian (n = 39,774) and BRCA1 mutation carrier (n = 11,705) cancer cases and controls. Leukocyte telomere measurements were also available for 53,724 participants. Most associations cluster into three independent peaks. The minor allele at the peak 1 SNP rs2736108 associates with longer telomeres (P = 5.8 × 10(-7)), lower risks for estrogen receptor (ER)-negative (P = 1.0 × 10(-8)) and BRCA1 mutation carrier (P = 1.1 × 10(-5)) breast cancers and altered promoter assay signal. The minor allele at the peak 2 SNP rs7705526 associates with longer telomeres (P = 2.3 × 10(-14)), higher risk of low-malignant-potential ovarian cancer (P = 1.3 × 10(-15)) and greater promoter activity. The minor alleles at the peak 3 SNPs rs10069690 and rs2242652 increase ER-negative (P = 1.2 × 10(-12)) and BRCA1 mutation carrier (P = 1.6 × 10(-14)) breast and invasive ovarian (P = 1.3 × 10(-11)) cancer risks but not via altered telomere length. The cancer risk alleles of rs2242652 and rs10069690, respectively, increase silencing and generate a truncated TERT splice variant.}, added-at = {2014-10-13T18:24:41.000+0200}, author = {Bojesen, Stig E. and Pooley, Karen A. and Johnatty, Sharon E. and Beesley, Jonathan and Michailidou, Kyriaki and Tyrer, Jonathan P. and Edwards, Stacey L. and Pickett, Hilda A. and Shen, Howard C. and Smart, Chanel E. and Hillman, Kristine M. and Mai, Phuong L. and Lawrenson, Kate and Stutz, Michael D. and Lu, Yi and Karevan, Rod and Woods, Nicholas and Johnston, Rebecca L. and French, Juliet D. and Chen, Xiaoqing and Weischer, Maren and Nielsen, Sune F. and Maranian, Melanie J. and Ghoussaini, Maya and Ahmed, Shahana and Baynes, Caroline and Bolla, Manjeet K. and Wang, Qin and Dennis, Joe and McGuffog, Lesley and Barrowdale, Daniel and Lee, Andrew and Healey, Sue and Lush, Michael and Tessier, Daniel C. and Vincent, Daniel and Bacot, Françis and Vergote, Ignace and Lambrechts, Sandrina and Despierre, Evelyn and Risch, Harvey A. and González-Neira, Anna and Rossing, Mary Anne and Pita, Guillermo and Doherty, Jennifer A. and Alvarez, Nuria and Larson, Melissa C. and Fridley, Brooke L. and Schoof, Nils and Chang-Claude, Jenny and Cicek, Mine S. and Peto, Julian and Kalli, Kimberly R. and Broeks, Annegien and Armasu, Sebastian M. and Schmidt, Marjanka K. and Braaf, Linde M. and Winterhoff, Boris and Nevanlinna, Heli and Konecny, Gottfried E. and Lambrechts, Diether and Rogmann, Lisa and Guénel, Pascal and Teoman, Attila and Milne, Roger L. and Garcia, Joaquin J. and Cox, Angela and Shridhar, Vijayalakshmi and Burwinkel, Barbara and Marme, Frederik and Hein, Rebecca and Sawyer, Elinor J. and Haiman, Christopher A. and Wang-Gohrke, Shan and Andrulis, Irene L. and Moysich, Kirsten B. and Hopper, John L. and Odunsi, Kunle and Lindblom, Annika and Giles, Graham G. and Brenner, Hermann and Simard, Jacques and Lurie, Galina and Fasching, Peter A. and Carney, Michael E. and Radice, Paolo and Wilkens, Lynne R. and Swerdlow, Anthony and Goodman, Marc T. and Brauch, Hiltrud and Garcia-Closas, Montserrat and Hillemanns, Peter and Winqvist, Robert and Dürst, Matthias and Devilee, Peter and Runnebaum, Ingo and Jakubowska, Anna and Lubinski, Jan and Mannermaa, Arto and Butzow, Ralf and Bogdanova, Natalia V. and Dörk, Thilo and Pelttari, Liisa M. and Zheng, Wei and Leminen, Arto and Anton-Culver, Hoda and Bunker, Clareann H. and Kristensen, Vessela and Ness, Roberta B. and Muir, Kenneth and Edwards, Robert and Meindl, Alfons and Heitz, Florian and Matsuo, Keitaro and {Du Bois}, Andreas and Wu, Anna H. and Harter, Philipp and Teo, Soo-Hwang and Schwaab, Ira and Shu, Xiao-Ou and Blot, William and Hosono, Satoyo and Kang, Daehee and Nakanishi, Toru and Hartman, Mikael and Yatabe, Yasushi and Hamann, Ute and Karlan, Beth Y. and Sangrajrang, Suleeporn and Kjaer, Susanne Krüger and Gaborieau, Valerie and Jensen, Allan and Eccles, Diana and Høgdall, Estrid and Shen, Chen-Yang and Brown, Judith and Woo, Yin Ling and Shah, Mitul and {Azmi, Mat Adenan Noor} and Luben, Robert and Omar, Siti Zawiah and Czene, Kamila and Vierkant, Robert A. and Nordestgaard, Børge G. and Flyger, Henrik and Vachon, Celine and Olson, Janet E. and Wang, Xianshu and Levine, Douglas A. and Rudolph, Anja and Weber, Rachel Palmieri and Flesch-Janys, Dieter and Iversen, Edwin and Nickels, Stefan and Schildkraut, Joellen M. and {Silva, Isabel Dos Santos} and Cramer, Daniel W. and Gibson, Lorna and Terry, Kathryn L. and Fletcher, Olivia and Vitonis, Allison F. and {van der Schoot, C Ellen} and Poole, Elizabeth M. and {Hogervorst, Frans B L} and Tworoger, Shelley S. and Liu, Jianjun and Bandera, Elisa V. and Li, Jingmei and Olson, Sara H. and Humphreys, Keith and Orlow, Irene and Blomqvist, Carl and Rodriguez-Rodriguez, Lorna and Aittomäki, Kristiina and Salvesen, Helga B. and Muranen, Taru A. and Wik, Elisabeth and Brouwers, Barbara and Krakstad, Camilla and Wauters, Els and Halle, Mari K. and Wildiers, Hans and Kiemeney, Lambertus A. and Mulot, Claire and Aben, Katja K. and Laurent-Puig, Pierre and Altena, Anne Mvan and Truong, Thérèse and {Massuger, Leon F A G} and Benitez, Javier and Pejovic, Tanja and {Perez, Jose Ignacio Arias} and Hoatlin, Maureen and Zamora, M. Pilar and Cook, Linda S. and Balasubramanian, Sabapathy P. and Kelemen, Linda E. and Schneeweiss, Andreas and Le, Nhu D. and Sohn, Christof and Brooks-Wilson, Angela and Tomlinson, Ian and Kerin, Michael J. and Miller, Nicola and Cybulski, Cezary and Henderson, Brian E. and Menkiszak, Janusz and Schumacher, Fredrick and Wentzensen, Nicolas and {Le Marchand}, Loic and Yang, Hannah P. and Mulligan, Anna Marie and Glendon, Gord and Engelholm, Svend Aage and Knight, Julia A. and Høgdall, Claus K. and Apicella, Carmel and Gore, Martin and Tsimiklis, Helen and Song, Honglin and Southey, Melissa C. and Jager, Agnes and {den Ouweland, Ans M Wvan} and Brown, Robert and {Martens, John W M} and Flanagan, James M. and Kriege, Mieke and Paul, James and Margolin, Sara and Siddiqui, Nadeem and Severi, Gianluca and Whittemore, Alice S. and Baglietto, Laura and McGuire, Valerie and Stegmaier, Christa and Sieh, Weiva and Müller, Heiko and Arndt, Volker and Labrèche, France and Gao, Yu-Tang and Goldberg, Mark S. and Yang, Gong and Dumont, Martine and McLaughlin, John R. and Hartmann, Arndt and Ekici, Arif B. and Beckmann, Matthias W. and Phelan, Catherine M. and Lux, Michael P. and Permuth-Wey, Jenny and Peissel, Bernard and Sellers, Thomas A. and Ficarazzi, Filomena and Barile, Monica and Ziogas, Argyrios and Ashworth, Alan and Gentry-Maharaj, Aleksandra and Jones, Michael and Ramus, Susan J. and Orr, Nick and Menon, Usha and Pearce, Celeste L. and Brüning, Thomas and Pike, Malcolm C. and Ko, Yon-Dschun and Lissowska, Jolanta and Figueroa, Jonine and Kupryjanczyk, Jolanta and Chanock, Stephen J. and Dansonka-Mieszkowska, Agnieszka and Jukkola-Vuorinen, Arja and Rzepecka, Iwona K. and Pylkäs, Katri and Bidzinski, Mariusz and Kauppila, Saila and Hollestelle, Antoinette and Seynaeve, Caroline and {Tollenaar, Rob A E M} and Durda, Katarzyna and Jaworska, Katarzyna and Hartikainen, Jaana M. and Kosma, Veli-Matti and Kataja, Vesa and Antonenkova, Natalia N. and Long, Jirong and Shrubsole, Martha and Deming-Halverson, Sandra and Lophatananon, Artitaya and Siriwanarangsan, Pornthep and Stewart-Brown, Sarah and Ditsch, Nina and Lichtner, Peter and Schmutzler, Rita K. and Ito, Hidemi and Iwata, Hiroji and Tajima, Kazuo and Tseng, Chiu-Chen and Stram, Daniel O. and {van den Berg, David} and Yip, Cheng Har and Ikram, M. Kamran and Teh, Yew-Ching and Cai, Hui and Lu, Wei and Signorello, Lisa B. and Cai, Qiuyin and Noh, Dong-Young and Yoo, Keun-Young and Miao, Hui and Iau, Philip Tsau-Choong and Teo, Yik Ying and McKay, James and Shapiro, Charles and Ademuyiwa, Foluso and Fountzilas, George and Hsiung, Chia-Ni and Yu, Jyh-Cherng and Hou, Ming-Feng and Healey, Catherine S. and Luccarini, Craig and Peock, Susan and Stoppa-Lyonnet, Dominique and Peterlongo, Paolo and Rebbeck, Timothy R. and Piedmonte, Marion and Singer, Christian F. and Friedman, Eitan and Thomassen, Mads and Offit, Kenneth and {Hansen, Thomas V O} and Neuhausen, Susan L. and Szabo, Csilla I. and Blanco, Ignacio and Garber, Judy and Narod, Steven A. and Weitzel, Jeffrey N. and Montagna, Marco and Olah, Edith and Godwin, Andrew K. and Yannoukakos, Drakoulis and Goldgar, David E. and Caldes, Trinidad and Imyanitov, Evgeny N. and Tihomirova, Laima and Arun, Banu K. and Campbell, Ian and Mensenkamp, Arjen R. and {van Asperen, Christi J} and {van Roozendaal, Kees E P} and Meijers-Heijboer, Hanne and Collée, J. Margriet and Oosterwijk, Jan C. and Hooning, Maartje J. and Rookus, Matti A. and {van der Luijt, Rob B} and {Os, Theo A Mvan} and Evans, D. Gareth and Frost, Debra and Fineberg, Elena and Barwell, Julian and Walker, Lisa and Kennedy, M. John and Platte, Radka and Davidson, Rosemarie and Ellis, Steve D. and Cole, Trevor and {Bressac-de Paillerets}, Brigitte and Buecher, Bruno and Damiola, Francesca and Faivre, Laurence and Frenay, Marc and Sinilnikova, Olga M. and Caron, Olivier and Giraud, Sophie and Mazoyer, Sylvie and Bonadona, Valérie and Caux-Moncoutier, Virginie and Toloczko-Grabarek, Aleksandra and Gronwald, Jacek and Byrski, Tomasz and Spurdle, Amanda B. and Bonanni, Bernardo and Zaffaroni, Daniela and Giannini, Giuseppe and Bernard, Loris and Dolcetti, Riccardo and Manoukian, Siranoush and Arnold, Norbert and Engel, Christoph and Deissler, Helmut and Rhiem, Kerstin and Niederacher, Dieter and Plendl, Hansjoerg and Sutter, Christian and Wappenschmidt, Barbara and Borg, Ake and Melin, Beatrice and Rantala, Johanna and Soller, Maria and Nathanson, Katherine L. and Domchek, Susan M. and Rodriguez, Gustavo C. and Salani, Ritu and Kaulich, Daphne Gschwantler and Tea, Muy-Kheng and Paluch, Shani Shimon and Laitman, Yael and Skytte, Anne-Bine and Kruse, Torben A. and Jensen, Uffe Birk and Robson, Mark and Gerdes, Anne-Marie and Ejlertsen, Bent and Foretova, Lenka and Savage, Sharon A. and Lester, Jenny and Soucy, Penny and Kuchenbaecker, Karoline B. and Olswold, Curtis and Cunningham, Julie M. and Slager, Susan and Pankratz, Vernon S. and Dicks, Ed and Lakhani, Sunil R. and Couch, Fergus J. and Hall, Per and {Monteiro, Alvaro N A} and Gayther, Simon A. and {Pharoah, Paul D P} and Reddel, Roger R. and Goode, Ellen L. and Greene, Mark H. and Easton, Douglas F. and Berchuck, Andrew and Antoniou, Antonis C. and Chenevix-Trench, Georgia and Dunning, Alison M.}, biburl = {https://www.bibsonomy.org/bibtex/2f542d6d9f6b8495bb3c69a1df6bba0fe/drtester}, interhash = {0324a79b5f4f40def3b6b38550a504c9}, intrahash = {f542d6d9f6b8495bb3c69a1df6bba0fe}, journal = {Nature genetics}, keywords = {Alternative_Splicing Breast_Neoplasms/etiology/pathology Case-Control_Studies Chromatin/genetics DNA_Methylation Female Gene_Expression_Profiling Genetic_Loci/genetics Genetic_Predisposition_to_Disease Genome-Wide_Association_Study Genotype Humans Luciferases/metabolism Oligonucleotide_Array_Sequence_Analysis Ovarian_Neoplasms/etiology/pathology Polymorphism,_Single_Nucleotide/genetics RNA,_Messenger/genetics Real-Time_Polymerase_Chain_Reaction Reverse_Transcriptase_Polymerase_Chain_Reaction Risk_Factors Telomerase/genetics Telomere/genetics Tumor_Markers,_Biological/genetics}, number = 4, pages = {371-84, 384e1-2}, timestamp = {2014-10-13T18:24:41.000+0200}, title = {Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer}, volume = 45, year = 2013 }