%0 Journal Article %1 nagylaki1974continuous %A Nagylaki, Thomas %A Crow, James F. %D 1974 %J Theoretical Population Biology %K components_of_selection differential_equations life_history population_genetics selection %N 2 %P 257-283 %R https://doi.org/10.1016/0040-5809(74)90045-8 %T Continuous selective models %U https://www.sciencedirect.com/science/article/pii/0040580974900458 %V 5 %X Neglecting age-structure, but taking into account matings with differential fertility in Mendelian reproduction, continuous selective models are formulated for a single locus with an arbitrary number of alleles, with or without distinguishing the sexes, and for two alleles at each of two loci in a monoecious population. In each case, without restricting the mating system, differential equations are derived for the genotypic frequencies, and the validity of the customary Malthusian-parameter differential equations for the gametic frequencies is established. Particular attention is devoted to the conditions for Hardy-Weinberg proportions under random mating. For multiple alleles at a single locus in a monoecious population, exact solutions are obtained for the following three Hardy-Weinberg models: gametic selection, no dominance, and the same selective effect for all alleles but one. The last scheme includes, as special cases, a completely dominant or recessive distinguished allele, and arbitrary selection with only two alleles. Two single-locus assortative mating patterns are analyzed for a monoecious organism using the general formalism. One of these has an arbitrary number of alleles, all the genotypes being distinguishable, while the other involves two alleles, one of which is completely dominant to the other.

@article{nagylaki1974continuous, abstract = {Neglecting age-structure, but taking into account matings with differential fertility in Mendelian reproduction, continuous selective models are formulated for a single locus with an arbitrary number of alleles, with or without distinguishing the sexes, and for two alleles at each of two loci in a monoecious population. In each case, without restricting the mating system, differential equations are derived for the genotypic frequencies, and the validity of the customary Malthusian-parameter differential equations for the gametic frequencies is established. Particular attention is devoted to the conditions for Hardy-Weinberg proportions under random mating. For multiple alleles at a single locus in a monoecious population, exact solutions are obtained for the following three Hardy-Weinberg models: gametic selection, no dominance, and the same selective effect for all alleles but one. The last scheme includes, as special cases, a completely dominant or recessive distinguished allele, and arbitrary selection with only two alleles. Two single-locus assortative mating patterns are analyzed for a monoecious organism using the general formalism. One of these has an arbitrary number of alleles, all the genotypes being distinguishable, while the other involves two alleles, one of which is completely dominant to the other.}, added-at = {2024-02-22T00:53:35.000+0100}, author = {Nagylaki, Thomas and Crow, James F.}, biburl = {https://www.bibsonomy.org/bibtex/283f31cad6f6304218cedc78b9cf8e67d/peter.ralph}, doi = {https://doi.org/10.1016/0040-5809(74)90045-8}, interhash = {2273aa0448f9403576139b54aa13cbc5}, intrahash = {83f31cad6f6304218cedc78b9cf8e67d}, issn = {0040-5809}, journal = {Theoretical Population Biology}, keywords = {components_of_selection differential_equations life_history population_genetics selection}, number = 2, pages = {257-283}, timestamp = {2024-02-22T00:53:35.000+0100}, title = {Continuous selective models}, url = {https://www.sciencedirect.com/science/article/pii/0040580974900458}, volume = 5, year = 1974 }