%0 Conference Paper %1 Frotscher2015 %A Frotscher, Ralf %A Staat, Manfred %B YIC GACM 2015, 3rd ECCOMAS Young Investigators Conference, 6th GACM Colloquium, Aachen, Germany, July 20-23, 2015 %C Aachen, Germany %D 2015 %E Elgeti, S. %E Simon, J.-W. %I RWTH Aachen %K cardiac coupling,finite element method tissue,electro-mechanical %T An electromechanical model for cardiac tissue constructs %U http://nbn-resolving.de/urn:nbn:de:hbz:82-rwth-2015-039806 %X The presented work computationally investigates cardiac tissue constructs, so-called engineered heart tissues, that consist of a collagen-based extracellular matrix and human-induced pluripotent stem-cell derived cardiomyocytes. A finite element model is built in order to support the interpretation of experimental results and to predict for instance the effect of drug application to the tissue. The electro-mechanically coupled model proves to be useful by means of elucidating macroscopic experimental results at the microscopic level.

@inproceedings{Frotscher2015, abstract = {The presented work computationally investigates cardiac tissue constructs, so-called engineered heart tissues, that consist of a collagen-based extracellular matrix and human-induced pluripotent stem-cell derived cardiomyocytes. A finite element model is built in order to support the interpretation of experimental results and to predict for instance the effect of drug application to the tissue. The electro-mechanically coupled model proves to be useful by means of elucidating macroscopic experimental results at the microscopic level.}, added-at = {2019-12-23T09:34:32.000+0100}, address = {Aachen, Germany}, author = {Frotscher, Ralf and Staat, Manfred}, biburl = {https://www.bibsonomy.org/bibtex/2a2145e6b98c80a556329b849c6f8d456/staat}, booktitle = {YIC GACM 2015, 3rd ECCOMAS Young Investigators Conference, 6th GACM Colloquium, Aachen, Germany, July 20-23, 2015}, editor = {Elgeti, S. and Simon, J.-W.}, interhash = {3e7c4d608ae1517c4a0fec10a3432c6c}, intrahash = {a2145e6b98c80a556329b849c6f8d456}, keywords = {cardiac coupling,finite element method tissue,electro-mechanical}, publisher = {RWTH Aachen}, timestamp = {2019-12-23T09:34:32.000+0100}, title = {{An electromechanical model for cardiac tissue constructs}}, url = {http://nbn-resolving.de/urn:nbn:de:hbz:82-rwth-2015-039806}, year = 2015 }