%0 Journal Article %1 malhotra-kumar_evaluation_2010 %A Malhotra-Kumar, Surbhi %A Heirstraeten, Liesbet Van %A Lee, Andie %A Abrahantes, Jose Cortinas %A Lammens, Christine %A Vanhommerig, Evelyn %A Molenberghs, Geert %A Aerts, Marc %A Harbarth, Stephan %A Goossens, Herman %A on behalf of the MOSAR WP2 Study Team, %D 2010 %J J. Clin. Microbiol. %K imported %N 12 %P 4598--4601 %R 10.1128/JCM.00004-10 %T Evaluation of Molecular Assays for Rapid Detection of Methicillin-Resistant Staphylococcus aureus %U http://jcm.asm.org/cgi/content/abstract/48/12/4598 %V 48 %X The diagnostic sensitivities of the BD GeneOhm and Cepheid Xpert assays were compared using culture on log-serial dilutions of well-characterized methicillin-resistant Staphylococcus aureus (MRSA) and non-MRSA strains and on nasal and groin swabs from patients with histories of MRSA carriage. The sensitivities of GeneOhm and Xpert were high at 103-CFU/ml MRSA concentrations (92.3\% and 96.3\%, respectively) although decreased considerably (\textless35\%) at a 1-log-lower concentration. Unexpectedly, both assays also detected select coagulase-negative staphylococci, which requires further evaluation.

@article{malhotra-kumar_evaluation_2010, abstract = {The diagnostic sensitivities of the {BD} {GeneOhm} and Cepheid Xpert assays were compared using culture on log-serial dilutions of well-characterized methicillin-resistant Staphylococcus aureus {(MRSA)} and {non-MRSA} strains and on nasal and groin swabs from patients with histories of {MRSA} carriage. The sensitivities of {GeneOhm} and Xpert were high at {103-CFU/ml} {MRSA} concentrations (92.3\% and 96.3\%, respectively) although decreased considerably ({\textless}35\%) at a 1-log-lower concentration. Unexpectedly, both assays also detected select coagulase-negative staphylococci, which requires further evaluation.}, added-at = {2011-03-11T10:05:34.000+0100}, author = {{Malhotra-Kumar}, Surbhi and Heirstraeten, Liesbet Van and Lee, Andie and Abrahantes, Jose Cortinas and Lammens, Christine and Vanhommerig, Evelyn and Molenberghs, Geert and Aerts, Marc and Harbarth, Stephan and Goossens, Herman and on behalf of the {MOSAR} {WP2} Study Team}, biburl = {https://www.bibsonomy.org/bibtex/28993eb029bad119629f2c1a32454e637/jelias}, doi = {10.1128/JCM.00004-10}, interhash = {43939e95ff436b8b05250802d1a2e386}, intrahash = {8993eb029bad119629f2c1a32454e637}, journal = {J. Clin. Microbiol.}, keywords = {imported}, month = dec, number = 12, pages = {4598--4601}, timestamp = {2011-03-11T10:05:59.000+0100}, title = {Evaluation of Molecular Assays for Rapid Detection of {Methicillin-Resistant} Staphylococcus aureus}, url = {http://jcm.asm.org/cgi/content/abstract/48/12/4598}, volume = 48, year = 2010 }