%0 Journal Article %1 Benyamini2010Flux %A Benyamini, Tomer %A Folger, Ori %A Ruppin, Eytan %A Shlomi, Tomer %D 2010 %I BioMed Central Ltd %J Genome Biology %K flux-analysis metabolic-networks %N 4 %P R43+ %R 10.1186/gb-2010-11-4-r43 %T Flux balance analysis accounting for metabolite dilution %U http://dx.doi.org/10.1186/gb-2010-11-4-r43 %V 11 %X Flux balance analysis is a common method for predicting steady-state flux distributions within metabolic networks, accounting for the growth demand for the synthesis of a predefined set of essential biomass precursors. Ignoring the growth demand for the synthesis of intermediate metabolites required for balancing their dilution leads flux balance analysis to false predictions in some cases. Here, we present metabolite dilution flux balance analysis, which addresses this problem, resulting in improved metabolic phenotype predictions.

@article{Benyamini2010Flux, abstract = {Flux balance analysis is a common method for predicting steady-state flux distributions within metabolic networks, accounting for the growth demand for the synthesis of a predefined set of essential biomass precursors. Ignoring the growth demand for the synthesis of intermediate metabolites required for balancing their dilution leads flux balance analysis to false predictions in some cases. Here, we present metabolite dilution flux balance analysis, which addresses this problem, resulting in improved metabolic phenotype predictions.}, added-at = {2018-12-02T16:09:07.000+0100}, author = {Benyamini, Tomer and Folger, Ori and Ruppin, Eytan and Shlomi, Tomer}, biburl = {https://www.bibsonomy.org/bibtex/2ce89ce4b6d73d1eda29c0e8271ded54e/karthikraman}, citeulike-article-id = {7040573}, citeulike-linkout-0 = {http://dx.doi.org/10.1186/gb-2010-11-4-r43}, citeulike-linkout-1 = {http://view.ncbi.nlm.nih.gov/pubmed/20398381}, citeulike-linkout-2 = {http://www.hubmed.org/display.cgi?uids=20398381}, day = 16, doi = {10.1186/gb-2010-11-4-r43}, interhash = {14be003e6e6c4621a07ccdf0bbde11b6}, intrahash = {ce89ce4b6d73d1eda29c0e8271ded54e}, issn = {1465-6906}, journal = {Genome Biology}, keywords = {flux-analysis metabolic-networks}, month = apr, number = 4, pages = {R43+}, pmid = {20398381}, posted-at = {2010-04-29 10:47:44}, priority = {2}, publisher = {BioMed Central Ltd}, timestamp = {2018-12-02T16:09:07.000+0100}, title = {Flux balance analysis accounting for metabolite dilution}, url = {http://dx.doi.org/10.1186/gb-2010-11-4-r43}, volume = 11, year = 2010 }