%0 Journal Article %1 taylor2001geneticdisease. %A Taylor, AE %A Yip, A %A Brayne, C %A Easton, D %A Evans, JG %A Xuereb, J %A Cairns, N %A Esiri, MM %A Rubinsztein, DC %C Department of Medical Genetics, Wellcome Trust Centre for Molecular Mechanisms in Disease, Cambridge Institute for Medical Research, Wellcome/MRC Building, Addenbrooke's Hospital, Hills Road, Cambridge CB2 2XY, UK. %D 2001 %J J Med Genet %K imported %N 4 %P 232--233 %T Genetic association of an LBP-1c/CP2/LSF gene polymorphism with late onset Alzheimer's disease. %U http://www.ncbi.nlm.nih.gov/pubmed/11283204 %V 38 %X The only locus unequivocally associated with late onset Alzheimer's disease (AD) risk is APOE. However, this locus accounts for less than half the genetic variance. A recent study suggested that the A allele of the 3'UTR biallelic polymorphism in the LBP-1c/CP2/LSF gene was associated with reduced AD risk. Samples were diagnosed predominantly by clinical rather than pathological criteria. We have sought to replicate this finding in a series of necropsy confirmed, late onset AD cases and non-demented controls.

@article{taylor2001geneticdisease., abstract = {The only locus unequivocally associated with late onset Alzheimer's disease (AD) risk is APOE. However, this locus accounts for less than half the genetic variance. A recent study suggested that the A allele of the 3'UTR biallelic polymorphism in the LBP-1c/CP2/LSF gene was associated with reduced AD risk. Samples were diagnosed predominantly by clinical rather than pathological criteria. We have sought to replicate this finding in a series of necropsy confirmed, late onset AD cases and non-demented controls.}, added-at = {2013-08-12T12:53:15.000+0200}, address = {Department of Medical Genetics, Wellcome Trust Centre for Molecular Mechanisms in Disease, Cambridge Institute for Medical Research, Wellcome/MRC Building, Addenbrooke's Hospital, Hills Road, Cambridge CB2 2XY, UK.}, author = {Taylor, AE and Yip, A and Brayne, C and Easton, D and Evans, JG and Xuereb, J and Cairns, N and Esiri, MM and Rubinsztein, DC}, biburl = {https://www.bibsonomy.org/bibtex/217a6fefdcb4ccaacf6c65197cb606ccb/sokratesagogo}, eissn = {1468-6244}, interhash = {4cbfa125abe6d91b374b75d8db30c592}, intrahash = {17a6fefdcb4ccaacf6c65197cb606ccb}, journal = {J Med Genet}, keyword = {Age of Onset}, keywords = {imported}, language = {eng}, month = Apr, note = {PMCID: PMC1734850}, number = 4, organization = {England}, pages = {232--233}, timestamp = {2013-08-12T12:53:34.000+0200}, title = {Genetic association of an LBP-1c/CP2/LSF gene polymorphism with late onset Alzheimer's disease.}, url = {http://www.ncbi.nlm.nih.gov/pubmed/11283204}, volume = 38, year = 2001 }